ArticleHaemophilia : the official journal of the World Federation of Hemophilia2025
Subjective Physical Performance and Its Determinants in Patients With Haemophilia.
Article in Haemophilia : the official journal of the World Federation of Hemophilia, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- The Psychometric Properties of the Moberg Pick-Up Test (MPUT) to Assess Fine Motor Skills in Adults with Haemophilia.Healthcare (Basel, Switzerland) · 2026Article
- Nurses at the helm of transforming lives in the shadows of Hemophilia.Bioinformation · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionPhysical functioning is compromised in patients with haemophilia (PwH). However, factors negatively influencing subjective physical performance (SPP) remain underexplored. Hence, this study aimed to compare the SPP of PwH with healthy controls (CON), to differentiate them based on disease-specific, person-related, and arthropathy-related parameters, and to identify overarching determinants influencing SPP.
methodsSPP was assessed in 301 PwH and 263 CON via the HEP-Test-Q, which divides SPP into a total score and four distinct dimensions (e.g., mobility). Additionally, disease-specific (i.e., type, severity, treatment regime, HIV, hepatitis), person-related (i.e., age, BMI), and arthropathy-related parameters (i.e., current pain intensity (NRS-now) and average pain intensity across 4 weeks (NRS-4w) and the HJHS) were examined, and associations with SPP were calculated.
resultsAll PwH and PwH subgroups demonstrated significantly greater impairment across all SPP dimensions compared to CON. Apart from the type of haemophilia (A vs. B, p = 0.894), significant differences in total SPP were observed among PwH subgroups for severity (severe vs. non-severe, p = 0.012), treatment (prophylaxis vs. on demand, p = 0.002), HIV (no vs. yes), and hepatitis (no vs. yes, both p < 0.001). A multiple linear regression model further revealed significant predictive effects for HJHS (p < 0.001) and NRS-4w (p < 0.001) on the total SPP score.
conclusionPwH perceived their physical performance as significantly worse across all dimensions compared to CON. The decreased SPP in PwH can be attributed primarily to arthropathy-related factors, that is, an impaired joint status and persistent pain. To oppose the decline in SPP, tailored sports-therapeutic programs should be integrated into the multimodal treatment concept.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.