Evidence map›Paper›PMID 40153305›Full record

ArticleeLife2025

Dimeric

Minsoo Noh, Xiangguo Che, Xian Jin, Dong-Kyo Lee, Hyun-Ju Kim, Doo Ri Park, Soo Young Lee, Hunsang Lee, Thomas J Gardella, Je-Yong Choi and 1 more

Abstract read
In one paragraph

Article in eLife, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
  4. Review
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Minsoo Noh *Department of Internal Medicine and Laboratory of Genomics and Translational Medicine, Gachon University College of Medicine, Incheon, Republic of Korea.ORCID https://orcid.org/0000-0002-1239-3783
Xiangguo Che *Department of Biochemistry and Cell Biology, Cell and Matrix Research Institute, School of Medicine, Kyungpook National University, Daegu, Republic of Korea.
Xian JinDepartment of Biochemistry and Cell Biology, Cell and Matrix Research Institute, School of Medicine, Kyungpook National University, Daegu, Republic of Korea.
Dong-Kyo LeeDepartment of Biochemistry and Cell Biology, Cell and Matrix Research Institute, School of Medicine, Kyungpook National University, Daegu, Republic of Korea.
Hyun-Ju KimDepartment of Biochemistry and Cell Biology, Cell and Matrix Research Institute, School of Medicine, Kyungpook National University, Daegu, Republic of Korea.
Doo Ri ParkDepartment of Life Sciences, Multitasking Macrophage Research Center, Ewha Womans University, Seoul, Republic of Korea.
Soo Young LeeDepartment of Life Sciences, Multitasking Macrophage Research Center, Ewha Womans University, Seoul, Republic of Korea.
Hunsang LeeDepartment of Life Sciences, Korea University, Seoul, Republic of Korea.
Thomas J GardellaEndocrine Unit, Massachusetts General Hospital and Harvard Medical School, Boston, United States.
Je-Yong ChoiDepartment of Biochemistry and Cell Biology, Cell and Matrix Research Institute, School of Medicine, Kyungpook National University, Daegu, Republic of Korea.
Sihoon LeeDepartment of Internal Medicine and Laboratory of Genomics and Translational Medicine, Gachon University College of Medicine, Incheon, Republic of Korea.ORCID https://orcid.org/0000-0002-9444-5849

Funding

Gachon University FRD2023-12National Research Foundation of Korea 2021R1A2C3003675National Research Foundation of Korea 2022R1A2C1006105National Research Foundation of Korea 2022R1A2C3006002National Research Foundation of Korea 2022R1A4A1025913National Research Foundation of Korea 2022R1F1A1074610National Research Foundation of Korea RS-2023-00217798
6 · The paper itself

Abstract

Osteoporosis, characterized by reduced bone density and strength, increases fracture risk, pain, and limits mobility. Established therapies of parathyroid hormone (PTH) analogs effectively promote bone formation and reduce fractures in severe osteoporosis, but their use is limited by potential adverse effects. In the pursuit of safer osteoporosis treatments, we investigated

Indexed as

OsteogenesisOsteoporosisParathyroid HormoneReceptor, Parathyroid Hormone, Type 1AnimalsBone DensityCyclic AMPFemaleHumansMiceCyclic AMPParathyroid HormoneReceptor, Parathyroid Hormone, Type 1bone formationgeneticsgenomicshumanmouseosteoporosisparathyroid hormonePTH type-1 receptor

Identifiers

PMID40153305
PMCPMC11952747

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.