Evidence map›Paper›PMID 40153230›Full record

ArticleDiabetes therapy : research, treatment and education of diabetes and related disorders2025

Preferences, Expectations and Attitudes on Basal Insulin from Patient-Physician-Payer Perspective: A Multi-stakeholder Survey by the Italian Diabetes Society (ITA4P Study).

Gian Paolo Fadini, Stefano Ciardullo, Gianluca Perseghin, Carla Giordano, Ernesto Maddaloni, Raffaella Buzzetti, Mariangela Ghiani, Angelo Avogaro

Abstract read
In one paragraph

Article in Diabetes therapy : research, treatment and education of diabetes and related disorders, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Gian Paolo FadiniDepartment of Medicine, Unit of Metabolic Diseases, University of Padova, via Giustiniani 2, 35128, Padua, Italy. gianpaolo.fadini@unipd.it.ORCID http://orcid.org/0000-0002-6510-2097
Stefano CiardulloDepartment of Medicine and Rehabilitation, Policlinico di Monza, Monza, Italy.
Gianluca PerseghinDepartment of Medicine and Rehabilitation, Policlinico di Monza, Monza, Italy.
Carla GiordanoSection of Endocrinology, Department of Health Promotion, Mother and Child Care, Internal Medicine and Medical Specialties "G. D'Alessandro" (PROMISE), University of Palermo, Palermo, Italy.
Ernesto MaddaloniDepartment of Experimental Medicine, Sapienza University of Rome, Rome, Italy.
Raffaella BuzzettiDepartment of Experimental Medicine, Sapienza University of Rome, Rome, Italy.
Mariangela GhianiDiabetology Service, ASL8 Quartu, Cagliari, Italy.
Angelo AvogaroDepartment of Medicine, Unit of Metabolic Diseases, University of Padova, via Giustiniani 2, 35128, Padua, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionDiabetes management often involves complex insulin regimens, posing significant challenges for patients and healthcare systems. Weekly basal insulin formulations aim to simplify treatment, reduce injection frequency, and improve adherence and quality of life. This study explored the beliefs, preferences and attitudes of patients, physicians and payers regarding current basal insulin therapy and weekly insulin formulations.

methodsAn online survey with structured questionnaires was developed for multiple stakeholders: patients with type 1 or type 2 diabetes, physicians and payers. Participants provided self-reported insights into basal insulin therapy and perceptions of weekly formulations. Results are presented in a descriptive non-analytical way.

resultsA total of 1094 patients, 468 physicians and 100 payers participated. Patients reported moderate satisfaction with current insulin therapy, with lower satisfaction in type 2 diabetes (T2D). The major burdens identified were daily injections and fear of hypoglycaemia, with weekly insulin seen as a promising alternative. Physicians prioritized glycaemic control goals, while patients emphasized independence and quality of life. Payers valued adherence and hypoglycaemia avoidance but raised concerns about costs and education needs.

conclusionsAccording to this multi-stakeholder survey, weekly basal insulin offers a promising approach to reduce treatment burden and improve adherence and quality of life. Addressing concerns about safety, efficacy and cost will be critical to its successful adoption in clinical practice.

Indexed as

AdherenceBasal insulinEfsitoraIcodecPatient-reported outcomesQuality of life

Identifiers

PMID40153230
PMCPMC12085408

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.