Evidence map›Paper›PMID 40153217›Full record

SynthesisReproductive sciences (Thousand Oaks, Calif.)2025

High Maternal Serum Uric Acid Levels and Risk of Low-Birth-Weight and Small for Gestational Age Infant: A Systematic Review and Meta-Analysis.

Khalid Khadawardi, Mohammed Abuzaid, Saeed Baradwan, Saud Owaimer Alsehaimi, Hedaya Albelwi, Seham Adel Arishi, Mooza M Alzayed, Osama Alomar, Ahmed Abu-Zaid

Abstract readSystematic ReviewMeta-Analysis
PubMed Publisher
In one paragraph

Synthesis in Reproductive sciences (Thousand Oaks, Calif.), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Khalid KhadawardiDepartment of Obstetrics and Gynecology, Faculty of Medicine, Umm Al-Qura University, Makkah, Saudi Arabia.
Mohammed AbuzaidDepartment of Obstetrics and Gynecology, Al Birk General Hospital, Al Birk, Saudi Arabia.
Saeed BaradwanDepartment of Obstetrics and Gynecology, King Faisal Specialist Hospital and Research Center, Jeddah, Saudi Arabia.
Saud Owaimer AlsehaimiDepartment of Obstetrics and Gynecology, King Faisal Specialist Hospital and Research Center, Riyadh, Saudi Arabia.
Hedaya AlbelwiDepartment of Obstetrics and Gynecology, National Guard Hospital, Riyadh, Saudi Arabia.
Seham Adel ArishiDepartment of Pediatric Intensive Care Unit, King Fahad Central Hospital, Jazan, Saudi Arabia.
Mooza M AlzayedCollege of Medicine and Medical Sciences, Arabian Gulf University, Manama, Bahrain.
Osama AlomarDepartment of Obstetrics and Gynecology, King Faisal Specialist Hospital and Research Center, Riyadh, Saudi Arabia.
Ahmed Abu-ZaidDepartment of Obstetrics and Gynecology, College of Medicine, Alfaisal University, Riyadh, Saudi Arabia. aabuzaid@live.com.ORCID 0000-0003-2286-2181

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Although the association between high uric acid levels and adverse pregnancy outcomes has been explored, the effects of elevated uric acid levels on the risk of low-birth-weight (LBW) and small for gestational age (SGA) remain unclear. Therefore, this systematic review and meta-analysis aimed to investigate the relationship between uric acid levels during pregnancy and the risk of LBW. PubMed, Scopus, Cochrane central and Web of Science databases were searched up to September 2024 for relevant observational studies. A random effects model was used to estimate pooled odds ratios (OR) and 95% confidence intervals (95% CI). To assess the heterogeneity of included studies, the I

Indexed as

HyperuricemiaInfant, Low Birth WeightInfant, Small for Gestational AgeUric AcidFemaleHumansInfant, NewbornPregnancyRisk FactorsUric AcidHyperuricemiaLow birth weightPregnancySmall for gestational ageUric acid

Identifiers

PMID40153217

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.