History of primary hypertrophic osteoarthropathy.

Ruiyao Hu, Xinbo Yu, Zhimin Lin, Shufeng Wei, Naigang Chen, Yiwei Guan, Chen Li

Abstract readCase Reports

In one paragraph

Article in Clinical rheumatology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it

0cells of the map it votes in

0citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Ruiyao Hu *Department of Rheumatology, Fangshan Hospital, Beijing University of Chinese Medicine, Beijing, China.

Xinbo Yu *School of Traditional Chinese Medicine, Beijing University of Chinese Medicine, Beijing, China.

Zhimin Lin *Third Affiliated Hospital, Beijing University of Chinese Medicine, Beijing, China.

Shufeng WeiDepartment of Rheumatology, Fangshan Hospital, Beijing University of Chinese Medicine, Beijing, China.

Naigang ChenDepartment of Imaging, Fangshan Hospital, Beijing University of Chinese Medicine, Beijing, China.

Yiwei GuanSchool of Chinese Materia Medica, Beijing University of Chinese Medicine, Beijing, China.

Chen LiDepartment of Rheumatology, Fangshan Hospital, Beijing University of Chinese Medicine, Beijing, China. casio1981@163.com.ORCID http://orcid.org/0000-0002-8527-1680

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Primary hypertrophic osteoarthropathy (PHO) is a rare systemic disorder characterized. by periosteal new bone formation, clubbing of fingers and toes, and thickening of the. skin, particularly on the forehead and face. This case study presents a 24-year-old. male patient with a decade-long history of prominent skin folds on the forehead and. face, joint swelling in hands and feet, and calf pain. Clinical manifestations included. progressive facial wrinkling, thickening of distal joints, and cortical thickening observed. on X-rays. Serum levels of insulin-like growth factor (IGF-1), thyroid function, rheumatoid factor, and anti-cyclic citrullinated peptide were within normal ranges. The diagnosis was confirmed through a comprehensive evaluation of clinical, radiological, and laboratory findings. This report underscores the importance of recognizing the. distinct features of PHO for accurate diagnosis and timely management.

Indexed as

Osteoarthropathy, Primary HypertrophicHumansInsulin-Like Growth Factor IMaleRadiographyYoung AdultInsulin-Like Growth Factor IInsulin-like growth factorPrimary hypertrophic osteoarthropathyThyroid function

Identifiers

PMID40153198

DOI10.1007/s10067-025-07405-z

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.