ArticleJournal of neuro-oncology2025
The association of hospital volume status with treatment and survival outcomes of intracranial meningioma patients: a multivariable analysis of the National Cancer Database.
Article in Journal of neuro-oncology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
1 citing paper in PubMed.
- Using data for novel discoveries in neuro-oncology research.Journal of neuro-oncology · 2025Review
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Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeThis study investigates the influence of treatment center volume on survival outcomes and treatment strategies for patients with intracranial meningioma.
methodsThis is a retrospective cohort study of patients from the National Cancer Database treated for intracranial meningioma from 2004 to 2019. High-volume facility was defined as performing > 45 meningioma procedures/year (top 15%). Logistic regression was used for categorical comparisons. All patients were assessed whether facility volume status was associated with survival outcomes using log-rank tests and a final adjusted Cox proportional hazards model.
results181,401 patients were included; 28,325 (15.6%) were treated at high-volume facilities, and 153,076 (84.4%) at low-volume facilities. In adjusted analyses, patients were more likely to be treated at high-volume facilities if they had private insurance status (OR = 1.25, 95% CI 1.21-1.29, p < 0.01) and higher tumor volume (OR = 1.11, 95% CI 1.07-1.14, p < 0.01). Patients treated at high-volume facilities were more likely to receive surgery (OR = 1.43, 95% CI 1.38-1.47, p < 0.01), radiotherapy (OR = 1.5, 95% CI 1.43-1.57, p < 0.01), stereotactic radiosurgery (OR = 1.56, 95% CI 1.48-1.65, p < 0.01), but were less likely to require readmission at 30 days (OR = 0.86, 95% CI 0.79-0.94, p = 0.01). On multivariable analysis, treatment at a high-volume facility was a positive predictor of survival (HR = 0.62, 95% CI 0.55 - 0.70, p < 0.01).
conclusionsMost meningiomas are treated at low-volume facilities. Patients treated at high-volume facilities are more likely to receive surgery, radiotherapy, and stereotactic radiosurgery are also more likely to have improved survival when compared to patients treated at low-volume facilities. These findings collectively indicate that patients with lower socioeconomic support may experience worse survival outcomes because they struggle to access care at high-volume facilities. This information should be taken into account when shaping future healthcare policies and designing upcoming multicenter studies on meningioma.
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