Evidence map›Paper›PMID 40153093›Full record

ArticleSleep & breathing = Schlaf & Atmung2025

Home sleep study nasal airflow patterns and epiglottic collapse during drug induced sleep endoscopy.

Abhay Sharma, Jacob Noel, B Tucker Woodson

Abstract read
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In one paragraph

Article in Sleep & breathing = Schlaf & Atmung, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

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0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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2 · The registry

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3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
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4 · The record

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5 · Who and what money

Authors and funding

3 authors.

Abhay SharmaDepartment of Otolaryngology-Head and Neck Surgery, University of South Florida Morsani College of Medicine, Tampa, Florida, USA. asharma2@usf.edu.ORCID 0000-0002-8041-4750
Jacob NoelDepartment of Otolaryngology and Human Communication, Medical College of Wisconsin, Milwaukee, Wisconsin, USA.ORCID 0000-0002-1614-6472
B Tucker WoodsonDepartment of Otolaryngology and Human Communication, Medical College of Wisconsin, Milwaukee, Wisconsin, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeObstructive sleep apnea (OSA) is characterized by collapse of various portions of the pharynx. Epiglottic collapse is difficult to diagnose and may affect treatment tolerance. Previous research shows a distinct nasal airflow pattern during epiglottic obstruction characterized by signal discontinuities. It was hypothesized that primary epiglottic collapse characterized during drug-induced sleep endoscopy (DISE) correlates with nasal airflow discontinuity signals seen on home sleep studies.

methodsPatients with clinical records of undergoing both DISE and home portable sleep studies with raw data available from December 2016 to August 2021 were screened for epiglottic collapse or no epiglottic collapse using the VOTE scoring system. Any patient with tongue base collapse was excluded. Characterization of nasal airflow signals as discontinuities was based on previously published data. Acute flow discontinuities were scored by two blinded observers (AS, JN) from home cardiorespiratory studies using nasal pressure cannulas (Apnea Link Plus). Breath statistics (total number of breaths and flow limited breaths) for each patient were captured by the home cardiorespiratory device. DISE was performed under propofol anesthesia to a Ramsay level 5. Epiglottic collapse was described by shape, direction (AP or lateral), and timing (prolonged or intermittent).

resultsThe home sleep studies and DISE of 18 patients being considered for surgical therapies were retrospectively analyzed. Patients included had either complete (n=11) or no epiglottic collapse (n=7). The mean AHI was 21.3 and 19.7, respectively. There was a significant difference between nonepiglottic and epiglottic collapse groups in the total discontinuity breaths (median 7 vs 29, p=0.002), discontinuity breaths/hour (median 0.91 vs 5.3, p=0.001), and fraction of discontinuity breaths over total flow limited breaths (0.5% vs 1.9%, p=0.001). Morphological changes in epiglottic collapse did not affect discontinuities.

conclusionThe data from this study demonstrates nasal airflow signals from home sleep studies correlate with DISE epiglottic collapse.

Indexed as

EndoscopyEpiglottisPolysomnographySleep Apnea, ObstructiveAdultAgedFemaleHumansMaleMiddle AgedDISEDrug-induced sleep endoscopyEpiglottic collapseObstructive sleep apneaOSA

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.