Evidence map›Paper›PMID 40153080›Full record

ReviewMolecular biology reports2025

The comprehensive review of eucalyptol: synthesis, metabolism, and therapeutic applications in disease treatment.

Bin Yao, Bin He, Jiahua Peng, Xin Song, Rui Zhao, Yu Sun, Yanfang Zhang

Abstract readReview
PubMed Publisher
In one paragraph

Review in Molecular biology reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Bin YaoAffiliated Hospital of Jiangxi University of Traditional Chinese Medicine, Nanchang, 330006, China.
Bin HeJiangxi Key Laboratory of Natural Microbial Medicine Research, College of Life Sciences, Jiangxi Science & Technology Normal University, Nanchang, 330013, China.
Jiahua PengJiangxi University of Traditional Chinese Medicine, Nanchang, 330004, China.
Xin SongJiangxi University of Traditional Chinese Medicine, Nanchang, 330004, China.
Rui ZhaoJiangxi Key Laboratory of Natural Microbial Medicine Research, College of Life Sciences, Jiangxi Science & Technology Normal University, Nanchang, 330013, China.
Yu SunJiangxi University of Traditional Chinese Medicine, Nanchang, 330004, China.
Yanfang ZhangShaoxing Seventh People's Hospital, Shaoxing, 312000, China. fangde2008@126.com.

Funding

the Jiangxi Provincial Key Laboratory of TCM Female Reproductive Health and Related Diseases Research and transformation No. 2024SSY06311the Jiangxi University of Chinese Medicine Science and Technology Innovation Team Development Program No. CXTD22013the National Natural Science Foundation of China No. 32260017the Science and technology plan of Jiangxi Provincial Administration of Traditional Chinese Medicine No. 2023B1071
6 · The paper itself

Abstract

backgroundEucalyptol (1,8-cineole), a naturally occurring monoterpenoid compound, is ubiquitously distributed across plant, animal, and microbial organisms. This bioactive molecule demonstrates significant therapeutic potential for various neurological and respiratory disorders, including cancer, epilepsy, and tracheitis, attributable to its potent antioxidant, anti-inflammatory, and antimicrobial properties. SCOPE AND THRUST: The present review systematically examines the biosynthetic pathways and metabolic routes of eucalyptol, while elucidating its molecular mechanisms underlying microbial inhibition. We comprehensively summarize its principal therapeutic pathways in major disease interventions, with particular emphasis on its multi-target pharmacological actions. Furthermore, this analysis addresses potential toxicological concerns associated with eucalyptol application and discusses emerging strategies utilizing biological agents for active enhancement. CONCLUSION AND SIGNIFICANCE: This comprehensive evaluation not only enhances our understanding of eucalyptol's therapeutic mechanisms but also provides critical insights for its development as a promising phytopharmaceutical agent in clinical practice.

Indexed as

EucalyptolAnimalsAnti-Infective AgentsAnti-Inflammatory AgentsAntioxidantsBiosynthetic PathwaysHumansNeoplasmsAnti-Infective AgentsAnti-Inflammatory AgentsAntioxidantsEucalyptolAnti-inflammatoryAnti-microbialEucalyptolNeurological disordersRespiratory diseases

Identifiers

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.