Trial reportSupportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer2025
Physiotherapy protocol to reduce the evolution time of axillary web syndrome in women post-breast cancer surgery: a randomized clinical trial.
Trial report in Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 3 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Effects of a Manual Therapy Program to Reduce the Evolution Time of Axillary Web Syndrome
Effects of Muscle Energy Techniques With and Without Manual Axial Distraction on Pain, Range of Motion Anf Functional Outcomes in Post-Mastectomy Patients With Axillary Web Syndrome
Who cites it
3 citing papers in PubMed.
- Axillary Web Syndrome Beyond Breast Cancer: Expanding the Clinical Spectrum Through Illustrative Cases and Contemporary Evidence.Journal of clinical medicine · 2026Article
- Hypertension as a confounding variable in axillary web syndrome recovery studies.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2025Article
- Protocol to improve quality of life, functionality, and exercise capacity in patients with axillary web syndrome after breast cancer: a randomized clinical trial.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2025Article
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo reduce the evolution time of axillary web syndrome in women who have undergone breast cancer surgery.
methodsA prospective, randomized, single-blind clinical trial was conducted on 46 post breast cancer surgery patients from October 2021 to September 2024, in a single university hospital with painful Axillary Web Syndrome (AWS) that restricts arm mobility. The treatment for the intervention group consisted of stretching combined with manual therapy and scar massage to release adhesion and lymphatic cord during 15 physiotherapy sessions of 30 min duration each. The main outcome measures were: healing time, pain, evaluated with Visual Analogue Scaler (VAS) and arm Range of Motion (ROM), evaluated with goniometry.
resultsSignificant differences were detected in pain and in ROM. The effect of the intervention varied over time with 95% confidence interval (risk alpha 0.05) and a statistical power of 90% (risk beta 0.1). Comparisons between Control and Intervention Groups showed significant statistical and clinical differences in favour of Intervention Group after 30, 60 and 90 days of intervention at follow-ups for all measured parameters. The proportion of healed patients was significantly higher in the intervention group from day 30 onwards (two-sample test for equality of proportions: p < 0.001), indicating a faster recovery in the intervention group.
conclusionThe results suggested that stretching combined with scar massage and manipulative tissue release techniques lead to a faster recovery and reduce the evolution time of axillary web syndrome. The physiotherapy technique described in this article could be the technique of choice for this surgical sequela.
trial registrationClinicalTrials.gov Registry (NCT05115799) on June 10th 2021 and the approval of the Andalucía Ethics Committee (PEIBA code 1909-N1-21, reg. number 171.21).
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.