ArticleSurgical endoscopy2025
Development and validation of a model for predicting electrocoagulation syndrome after endoscopic full-thickness resection of gastric tumors.
Article in Surgical endoscopy, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
backgroundPost-endoscopic submucosal dissection electrocoagulation syndrome (PEECS) is one of the postoperative adverse events of endoscopic resection, but the incidence and risk factors of PEECS after endoscopic full-thickness resection (EFTR) are still unclear. The purpose of this study was to identify risk factors and develop a predictive nomogram for PEECS after gastric EFTR. MATERIALS AND
methodsMultivariate logistic regression was used to analyze the risk factors of electrocoagulation syndrome after gastric EFTR. A prediction nomogram was developed based on the above results, and bootstrap was employed for internal validation of the model.
results507 patients who underwent gastric EFTR were included, and the incidence of PEECS was 9.9%. Multivariate analysis showed that tumor size ≥ 10 mm, hot biopsy forceps for hemostasis, and operation time were independent risk factors of PEECS. A nomogram based on these risk factors showed good predictive ability, and the area under the ROC curve (AUC) was 0.769 (95% CI: 0.700-0.838). The calibration curve of the predictive model also demonstrated a good fit.
conclusionThis study developed a predictive nomogram based on tumor size, hemostasis method, and operation time, which was used to identify high-risk patients with electrocoagulation syndrome after gastric EFTR.
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