Evidence map›Paper›PMID 40152627›Full record

ArticleJournal of veterinary internal medicine

Fungal Rhinosinusitis in Cats in the United Kingdom: 34 Cases (2013-2022).

Oliver Luke Russell, Daisy Johnson, Frederik Allan, Cameron Prior, Erin O'Connell, Perrine Henry, Daniel Thompson, Jack Fawsitt, Claudia Gil Morales, Victoria Neale and 4 more

Abstract readMulticenter StudyObservational Study, Veterinary
In one paragraph

Article in Journal of veterinary internal medicine. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. SinonasalThe Canadian veterinary journal = La revue veterinaire canadienne · 2026
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Oliver Luke RussellQueen's Veterinary School Hospital, University of Cambridge, Cambridge, UK.ORCID https://orcid.org/0009-0003-0205-4678
Daisy JohnsonQueen's Veterinary School Hospital, University of Cambridge, Cambridge, UK.
Frederik AllanNorth Downs Specialist Referrals, Bletchingley, UK.ORCID https://orcid.org/0000-0002-2275-8563
Cameron PriorWillows Veterinary Centre and Referral Service, Referral Service, Solihull, UK.
Erin O'ConnellSmall Animal Teaching Hospital, University of Liverpool, Neston, UK.
Perrine HenryThe Hospital for Small Animals, University of Edinburgh, Roslin, UK.ORCID https://orcid.org/0000-0003-1630-9080
Daniel ThompsonDavies Veterinary Specialists, Hitchin, UK.
Jack FawsittQueen's Veterinary School Hospital, University of Cambridge, Cambridge, UK.
Claudia Gil MoralesLangford Vets, University of Bristol, Langford, UK.ORCID https://orcid.org/0000-0002-6820-5876
Victoria NealeAnderson-Moores Veterinary Specialists, Winchester, UK.
Irene Strelitzia Garcia MolinaSouthfields Veterinary Specialists, Basildon, UK.
Harriet HallDick White Referrals, Six Mile Bottom, UK.ORCID https://orcid.org/0000-0003-2892-6748
Ruth GostelowRoyal Veterinary College, University of London, Hatfield, UK.ORCID https://orcid.org/0000-0001-9354-8291
Andre KortumQueen's Veterinary School Hospital, University of Cambridge, Cambridge, UK.ORCID https://orcid.org/0000-0002-9760-733X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundFungal rhinosinusitis in cats is an uncommon condition with sparse literature regarding the presentation, causative agents, diagnosis, treatment, and prognosis within the UK. HYPOTHESIS/

objectivesTo describe and report the presenting clinical signs, diagnostic imaging findings, treatment approach, and outcome of cats diagnosed with fungal rhinosinusitis in the UK. ANIMALS: Thirty-four client-owned cats were diagnosed with fungal rhinosinusitis.

methodsRetrospective multicenter observational study. Cases presenting at 10 UK referral centers between January 2013 and December 2022 were retrospectively recruited.

resultsMedian duration of clinical signs was 3 months (0.5-42-months). The most common signs were sneezing (27/34, 79%) and nasal discharge (21/34, 62%). Turbinate lysis was present in 27/34 cases (79%) and always involved the caudal nasal cavity. Osteolysis of the frontal bone, orbit, or cribriform plate was observed in 16/34 cases (47%). At least two tests from fungal culture, panfungal PCR, and histopathology were performed in all cases, and in 8/34 cases (24%) only one was positive. The treatment approach varied, with debridement, topical clotrimazole, and systemic azole therapy used alone or in various combinations, and repeat treatment occurred in 9/34 cases (26%). Clinical remission > 90 days after treatment was found in 9/24 cases (38%), but case fatality rates were low, with 3/34 cases (9%) dying with clinical disease during available follow-up. CONCLUSIONS AND CLINICAL IMPORTANCE: Fungal rhinosinusitis should be considered in cats of any age with clinical signs of nasal disease. The prognosis from this data appears guarded for cats with fungal rhinosinusitis, with less than 50% of cats achieving long-term clinical remission.

Indexed as

Cat DiseasesMycosesRhinitisSinusitisAnimalsAntifungal AgentsCatsDebridementFemaleMaleRetrospective StudiesRhinosinusitisUnited KingdomAntifungal Agentsaspergilluscryptococcusnasalrhinitissinusitis

Identifiers

PMID40152627
PMCPMC11951302

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.