Evidence map›Paper›PMID 40152616›Full record

ArticlemSystems2025

Phages-bacteria interactions underlying the dynamics of polyhydroxyalkanoate-producing mixed microbial cultures via meta-omics study.

Jian Yao, Yan Zeng, Xia Hong, Meng Wang, Quan Zhang, Yating Chen, Min Gou, Zi-Yuan Xia, Yue-Qin Tang

Abstract read
In one paragraph

Article in mSystems, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Hawaiian Geothermal Fumaroles Contain Diverse and Novel Viruses.bioRxiv : the preprint server for biology · 2026
    Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Jian YaoCollege of Architecture and Environment, Sichuan University, , Chengdu, Sichuan, China.ORCID 0000-0003-3121-4223
Yan ZengCollege of Architecture and Environment, Sichuan University, , Chengdu, Sichuan, China.
Xia HongSinopec Shanghai Engineering Co. Ltd., Shanghai, China.
Meng WangSinopec (Dalian) Research Institute of Petroleum and Petrochemicals Co. Ltd., Dalian, Liaoning, China.
Quan ZhangSinopec (Dalian) Research Institute of Petroleum and Petrochemicals Co. Ltd., Dalian, Liaoning, China.
Yating ChenSichuan Environmental Protection Key Laboratory of Organic Wastes Valorization, Chengdu, Sichuan, China.
Min GouCollege of Architecture and Environment, Sichuan University, , Chengdu, Sichuan, China.
Zi-Yuan XiaCollege of Architecture and Environment, Sichuan University, , Chengdu, Sichuan, China.
Yue-Qin TangCollege of Architecture and Environment, Sichuan University, , Chengdu, Sichuan, China.ORCID 0000-0001-6872-1099

Funding

China Petrochemical Corporation No. 421063-10
6 · The paper itself

Abstract

The dynamics of the structure of polyhydroxyalkanoate-producing mixed microbial cultures (PHA-MMCs) during enrichment and maintenance is an unsolved problem. The effect of phages has been proposed as a cause of dynamic changes in community structure, but evidence is lacking. To address this question, five PHA-MMCs were enriched, and biological samples were sampled temporally to study the interactions between phage and bacterial members by combining metagenomics and metatranscriptomics. A total of 963 metagenome-assembled genomes (MAGs) and 4,294 phage operational taxonomic units (pOTUs) were assembled from bulk metagenomic data. The dynamic changes in the structure of phage and bacterial communities were remarkably consistent. Structural equation modeling analysis showed that phages could infect and lyse dominant species to vacate ecological niches for other species, resulting in a community succession state in which dominant species alternated. Seven key auxiliary metabolic genes (AMGs),

Indexed as

BacteriaBacteriophagesPolyhydroxyalkanoatesMetagenomeMetagenomicsPolyhydroxyalkanoatesauxiliary metabolic genes (AMGs)community assemblymicrobial community structure dynamicsmixed microbial cultures (MMCs)phages-bacteria interactionsphages-host dynamicspolyhydroxyalkanoates (PHAs)

Identifiers

PMID40152616
PMCPMC12013262

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.