Evidence map›Paper›PMID 40152592›Full record

ArticleGenetics2025

Yeast molecular genetic tricks to study gene regulation.

Kevin Struhl

Abstract readHistorical Article
In one paragraph

Article in Genetics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

Kevin StruhlDepartment of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Harvard University, Boston, MA 02115, USA.ORCID 0000-0002-4181-7856

Funding

Mechanism of yeast gene regulationR35GM131801 · NIGMS · HARVARD MEDICAL SCHOOL · PI KEVIN STRUHL · 2019 to 2026
$6.4M
NIGMS NIH HHS R35 GM131801NIH HHS GM131801
6 · The paper itself

Abstract

The Genetics Society of America's (GSA) Edward Novitski Prize is awarded to researchers for extraordinary creativity and intellectual ingenuity in genetics research. Struhl is being recognized for his pioneering work cloning a functional eukaryotic gene in E. coli, defining its promoter and regulatory region, and using random DNA and amino acid sequences to define determinants of specificity. The award also recognizes other key scientific contributions including Struhl's discovery of the sequences and protein interactions required for transcriptional activation and repression and demonstrating the importance of nucleosome-free regions for transcription initiation, among others.

Indexed as

Gene Expression Regulation, FungalSaccharomyces cerevisiaeAwards and PrizesHistory, 20th CenturyHistory, 21st Century

Identifiers

PMID40152592
PMCPMC13031115

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.