Evidence map›Paper›PMID 40152591›Full record

ArticlemSphere2025

The essential kinase TgGSK regulates centrosome segregation and endodyogeny in

Amanda Krueger, Sofia Horjales, Chunlin Yang, William J Blakely, Maria E Francia, Gustavo Arrizabalaga

Abstract read
In one paragraph

Article in mSphere, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. The Centrocone Protein SMC_N1 Is Important for the Proliferation ofAnimals : an open access journal from MDPI · 2026
    Article
  2. Article
  3. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors.

Amanda Krueger *Department of Pharmacology and Toxicology, Indiana University School of Medicine, Indianapolis, Indiana, USA.
Sofia Horjales *Laboratory of Apicomplexan Biology, Institut Pasteur de Montevideo, Montevideo, , Uruguay.
Chunlin YangDepartment of Pharmacology and Toxicology, Indiana University School of Medicine, Indianapolis, Indiana, USA.
William J BlakelyDepartment of Pharmacology and Toxicology, Indiana University School of Medicine, Indianapolis, Indiana, USA.
Maria E FranciaLaboratory of Apicomplexan Biology, Institut Pasteur de Montevideo, Montevideo, , Uruguay.ORCID 0000-0001-9664-9573
Gustavo ArrizabalagaDepartment of Pharmacology and Toxicology, Indiana University School of Medicine, Indianapolis, Indiana, USA.ORCID 0000-0002-4445-0375

Funding

Interleukin-1 and Steroid Signaling Drive Toxoplasma-induced Prostatic HyperplasiaR01DK124067 · NIDDK · INDIANA UNIVERSITY INDIANAPOLIS · PI ARRIZABALAGA, GUSTAVO A, JERDE, TRAVIS J · 2020 to 2023
$2.1M
Regulation of mitochondrial morphodynamics in Toxoplasma gondiiR01AI149766 · NIAID · STATE UNIVERSITY OF NEW YORK AT BUFFALO · PI ARRIZABALAGA, GUSTAVO A · 2020 to 2024
$2.0M
Homologs of brassinosteroid signaling proteins in Toxoplasma gondii regulate parasite divisionR21AI164619 · NIAID · INDIANA UNIVERSITY INDIANAPOLIS · PI ARRIZABALAGA, GUSTAVO A · 2021 to 2022
$436k
National Institute of Allergy and Infectious Diseases R01AI149766National Institute of Allergy and Infectious Diseases R21AI164619NIAID NIH HHS R01 AI149766NIAID NIH HHS R21 AI164619NIDDK NIH HHS R01 DK124067
6 · The paper itself

Abstract

Intracellular replication is crucial for the success of apicomplexan parasites, including IMPORTANCE: While infection with the parasite

Indexed as

CentrosomeProtozoan ProteinsToxoplasmaCell DivisionHumansPhosphorylationProtozoan Proteins

Identifiers

PMID40152591
PMCPMC12039231

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.