Evidence map›Paper›PMID 40152585›Full record

ArticlemBio2025

Differential crosstalk between toxin-immunity protein homologs divides

Feng Wang, Jing Luo, Zheng Zhang, Ya Liu, Duo Hong Sheng, Li Zhuo, Yue-Zhong Li

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in mBio, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors.

Feng WangState Key Laboratory of Microbial Technology, Institute of Microbial Technology, Shandong University, Qingdao, China.ORCID 0000-0003-4738-2029
Jing LuoState Key Laboratory of Microbial Technology, Institute of Microbial Technology, Shandong University, Qingdao, China.
Zheng ZhangState Key Laboratory of Microbial Technology, Institute of Microbial Technology, Shandong University, Qingdao, China.ORCID 0000-0001-9971-6006
Ya LiuState Key Laboratory of Microbial Technology, Institute of Microbial Technology, Shandong University, Qingdao, China.
Duo Hong ShengState Key Laboratory of Microbial Technology, Institute of Microbial Technology, Shandong University, Qingdao, China.ORCID 0000-0002-3044-8557
Li ZhuoState Key Laboratory of Microbial Technology, Institute of Microbial Technology, Shandong University, Qingdao, China.ORCID 0000-0001-8800-8688
Yue-Zhong LiState Key Laboratory of Microbial Technology, Institute of Microbial Technology, Shandong University, Qingdao, China.ORCID 0000-0001-8336-6638

Funding

JST | Natural Science Foundation of Jiangsu Province(Jiangsu Natural Science Foundation) BK20230248MOST | National Natural Science Foundation of China (NSFC) 32070030MOST | National Natural Science Foundation of China (NSFC) 32270073Natural Science Foundation of Shandong Province () ZR2022QC001Science & Technology Fundamental Resources Investigation Program 2022FY101100
6 · The paper itself

Abstract

Many bacteria discriminate self and nonself using toxins and their corresponding immunity proteins. The toxin-immunity systems often include homologs, potentially creating crosstalk with unknown influences on kin discrimination. In this study, we investigated the kinship controlled by four homologous toxin-immunity systems in the social bacterium

Indexed as

Bacterial ProteinsBacterial ToxinsMyxococcus xanthusToxin-Antitoxin SystemsMicrobial InteractionsBacterial ProteinsBacterial Toxinsclose and distant relationshipcross-immunitykin discriminationmultiple homologous pairsMyxococcus xanthustoxin–immunity protein system

Identifiers

PMID40152585
PMCPMC12077131

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.