ArticleJournal of clinical laboratory analysis2025
Risk Factors and Clinical Value of Deep Venous Thrombosis After Traumatic Lower Limb Fractures.
Article in Journal of clinical laboratory analysis, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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Who cites it
6 citing papers in PubMed.
- The role of ginkgo leaf extract and dipyridamole adjuvant treatment for reduction of lower limb deep vein thrombosis after proximal femoral nail antirotation surgery in elderly patients with intertrochanteric femoral fracture.Frontiers in pharmacology · 2026Article
- Correlation between red blood cell distribution width and deep vein thrombosis in patients with lower limb fractures.Frontiers in cardiovascular medicine · 2026Article
- Dynamic Evolution Characteristics and Nursing Intervention Windows of Perioperative Deep Vein Thrombosis in Patients with Lower Extremity Traumatic Fractures: A Prospective Cohort Study.Therapeutics and clinical risk management · 2026Article
- Risk Factors for Deep Vein Thrombosis in Hospitalized Patients With Periarticular Knee Fractures Caused by High-Energy Injuries.Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/HemostasisArticle
- Perioperative Deep Vein Thrombosis in Elderly Patients with Lower Extremity Fracture: A Comprehensive Review of Anesthetic Management Strategies.Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/HemostasisReview
- Application of Novel Thrombosis Scale in Fracture Related Lower Extremity Deep Venous Thrombosis.Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/HemostasisArticle
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4 authors.
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Abstract
objectiveDeep vein thrombosis (DVT) is a common complication after traumatic lower limb fractures. This study aims to investigate the risk factors associated with DVT after traumatic lower limb fractures and to analyze their values in clinical practice.
methodsPatients were classified into DVT and Non-DVT groups based on the occurrence of DVT during the perioperative period. These data were statistically analyzed to screen for risk factors for DVT after traumatic lower limb fractures and to analyze thrombus regression 1 month after surgery.
resultsDVT occurred in 39.29% (77/196) patients during the perioperative period. The incidence of DVT varied, with a high incidence of 46.67% for femoral neck/trochanteric fractures. Patients in the DVT group were characterized by older age, higher perioperative blood transfusion (both p < 0.001), higher fibrinogen (FIB) on admission (p < 0.001), significant postoperative Hb decline (p = 0.023) and higher D-D (p = 0.001). Age greater than 65 years, comorbid diabetes mellitus, and postoperative Hb decline of 30 g/L were independent risk factors for DVT in the perioperative period in patients with traumatic lower limb fractures. For every 1 SD increase in FIB and D-D, patients had a 1.01-fold (95% CI, 0.99 to 4.25) and 2.75-fold (95% CI, 1.055 to 7.25) increased risk of DVT, respectively.
conclusionDVT complicating traumatic lower limb fractures is strongly associated with a variety of risk factors, of which advanced age and significantly higher D-D on admission are two of the most critical.
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