Evidence map›Paper›PMID 40151611›Full record

ArticleFood science and biotechnology2025

Anticancer effects of purple carrot extract via induction of apoptotic genes on human breast cancer cells.

Ha Young Park, Sunhye Lee, So Hee Kim, Jung Eun Park, Youn Seon Hwang, Min Ho Kang, Seo Yeon Chae, Jin Woo Kim

Abstract read
In one paragraph

Article in Food science and biotechnology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Ha Young Park *Department of Food Science, Sunmoon University 70, Sunmoon-Ro 221 Beon-Gil, Tangjeong-Myeon, Asan-Si, Chungcheongnam-Do Korea.
Sunhye Lee *Department of Food Science, Sunmoon University 70, Sunmoon-Ro 221 Beon-Gil, Tangjeong-Myeon, Asan-Si, Chungcheongnam-Do Korea.
So Hee KimDepartment of Food Science, Sunmoon University 70, Sunmoon-Ro 221 Beon-Gil, Tangjeong-Myeon, Asan-Si, Chungcheongnam-Do Korea.
Jung Eun ParkDepartment of Food Science, Sunmoon University 70, Sunmoon-Ro 221 Beon-Gil, Tangjeong-Myeon, Asan-Si, Chungcheongnam-Do Korea.
Youn Seon HwangDepartment of Food Science, Sunmoon University 70, Sunmoon-Ro 221 Beon-Gil, Tangjeong-Myeon, Asan-Si, Chungcheongnam-Do Korea.
Min Ho KangDepartment of Food Science, Sunmoon University 70, Sunmoon-Ro 221 Beon-Gil, Tangjeong-Myeon, Asan-Si, Chungcheongnam-Do Korea.
Seo Yeon ChaeDepartment of Food Science, Sunmoon University 70, Sunmoon-Ro 221 Beon-Gil, Tangjeong-Myeon, Asan-Si, Chungcheongnam-Do Korea.
Jin Woo KimDepartment of Food Science, Sunmoon University 70, Sunmoon-Ro 221 Beon-Gil, Tangjeong-Myeon, Asan-Si, Chungcheongnam-Do Korea.ORCID 0000-0003-2108-287X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study investigated the anticancer effects of purple carrot extract (PCE) and its key bioactive substance, chlorogenic acid (CHA), on MDA-MB-231 cells and elucidated the mechanisms of apoptosis and anticancer activity. The effects of CHA treatment on the growth of HEK-293 and MDA-MB-231 cells were assessed, and CHA selectively inhibited the growth of MDA-MB-231, indicating specific inhibitory effect on breast cancer. When PCE and CHA were treated to MDA-MB-231 cells, an increase in in the expression of apoptosis-related genes and proteins, including

Indexed as

AnticancerApoptosisBreast cancerChlorogenic acidPurple carrot

Identifiers

PMID40151611
PMCPMC11937481

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.