Evidence map›Paper›PMID 40151609›Full record

ArticleFood science and biotechnology2025

Protective effects of carotenoids against blue light induced-cellular damage in human retinal pigment epithelium.

Jong Hoon Won, Dmitri Sitnikov, Jina Hong

Abstract read
In one paragraph

Article in Food science and biotechnology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Jong Hoon WonAmway Corporation, Amway I&S, 7575 Fulton St E, Ada, MI 49355 USA.
Dmitri SitnikovAmway Corporation, Amway I&S, 7575 Fulton St E, Ada, MI 49355 USA.
Jina HongNutrilite Health Institute, Amway I&S, 5600 Beach Blvd, Buena Park, CA 90621 USA.ORCID 0000-0002-8867-3431

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The retinal pigmented epithelium (RPE) is constantly exposed to visible light, including blue light (BL) that creates reactive oxygen species (ROS), which are harmful to DNA and induce cellular senescence. Carotenoids are recognized for their antioxidant properties, but their protective effect on DNA repair and cellular senescence under BL induced oxidative stress has not been evaluated. After BL irradiation, the positive senescence-associated-β-galactosidase (SA-β-gal) staining, and gene expression of Supplementary Information: The online version contains supplementary material available at 10.1007/s10068-024-01757-z.

Indexed as

ARPE-19Blue-lightCellular senescenceDNA damageOxidative stress

Identifiers

PMID40151609
PMCPMC11936865

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.