Evidence map›Paper›PMID 40151577›Full record

ReviewGeriatric orthopaedic surgery & rehabilitation2025

Fracture-Related Infection of the Proximal Femur - Diagnostics and Treatment.

Moritz Riedl, Josina Straub, Nike Walter, Susanne Baertl, Florian Baumann, Volker Alt, Markus Rupp

Abstract readReview
In one paragraph

Review in Geriatric orthopaedic surgery & rehabilitation, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Moritz RiedlDepartment of Trauma Surgery, University Medical Center Regensburg, Regensburg, Germany.
Josina StraubDepartment of Trauma Surgery, University Medical Center Regensburg, Regensburg, Germany.
Nike WalterDepartment of Trauma Surgery, University Medical Center Regensburg, Regensburg, Germany.
Susanne BaertlDepartment of Trauma Surgery, University Medical Center Regensburg, Regensburg, Germany.
Florian BaumannDepartment of Trauma Surgery, University Medical Center Regensburg, Regensburg, Germany.
Volker AltDepartment of Trauma Surgery, University Medical Center Regensburg, Regensburg, Germany.ORCID https://orcid.org/0000-0003-0208-4650
Markus RuppDepartment of Trauma Surgery, University Medical Center Regensburg, Regensburg, Germany.ORCID https://orcid.org/0000-0001-7221-3783

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpose: With the aging population and rising life expectancy the incidence of trauma-related injuries, particularly proximal femur fractures, is expected to increase. Complications such as fracture-related infections (FRI) significantly impede the healing process and pose substantial risks to patients. Despite advancements in understanding, diagnosing, and treating FRI, challenges persist in achieving optimal outcomes. This review addresses the significance of FRI following proximal femur fractures, emphasizing diagnostic methodologies and therapeutic modalities to enhance clinical care. Findings: Notably, a consensus definition for FRI has been established, providing clarity for accurate diagnosis. Diagnostic criteria encompass confirmatory and suggestive elements, facilitating precise identification of FRI. Therapeutic strategies for FRI in proximal femur fractures include a spectrum of surgical and antimicrobial approaches. Surgical interventions, ranging from debridement with implant retention over implant removal/exchange to staged conversions to arthroplasty, are tailored based on fracture stability, individual patient factors, and infection characteristics. The intricate decision-making process is elucidated, highlighting the importance of individualized treatment plans and multidisciplinary collaboration. Antimicrobial therapy plays a pivotal role in FRI management, with empirical regiments targeting common pathogens and local delivery systems offering sustained antibiotic release. Microbiological analysis and collaboration with infectious disease specialists should guide antimicrobial treatment and ensure optimal therapy efficacy. Conclusion: Managing FRI following proximal femur fractures requires a tailored, multidisciplinary approach. Treatment strategies should be guided by diagnostic precision, patient-specific considerations, and collaboration among surgical, infectious disease, and clinical teams. Implementing comprehensive therapeutic approaches is essential for mitigating the impact of FRI and improving patient outcomes.

Indexed as

complicationfracture-related infectionimplant-associated infectionproximal femur fracture

Identifiers

PMID40151577
PMCPMC11948549

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.