Evidence map›Paper›PMID 40151536›Full record

ArticleRSC advances2025

Nanocomplexation between curcumin and proteins by charge-switch method for improved physicochemical and biological properties of curcumin.

Anyu Zhang, Manish Mahotra, Hong Yu, Tianqi Zhu, Say Chye Joachim Loo

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in RSC advances, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Anyu ZhangSchool of Materials Science and Engineering, Nanyang Technological University 50 Nanyang Avenue 639798 Singapore joachimloo@ntu.edu.sg.
Manish MahotraSchool of Materials Science and Engineering, Nanyang Technological University 50 Nanyang Avenue 639798 Singapore joachimloo@ntu.edu.sg.
Hong YuSchool of Materials Science and Engineering, Nanyang Technological University 50 Nanyang Avenue 639798 Singapore joachimloo@ntu.edu.sg.
Tianqi ZhuSchool of Materials Science and Engineering, Nanyang Technological University 50 Nanyang Avenue 639798 Singapore joachimloo@ntu.edu.sg.
Say Chye Joachim LooSchool of Materials Science and Engineering, Nanyang Technological University 50 Nanyang Avenue 639798 Singapore joachimloo@ntu.edu.sg.ORCID https://orcid.org/0000-0001-5300-1275

Funding

EPA EP-C-14-005
6 · The paper itself

Abstract

Curcumin, a natural polyphenol, has various biological functions including antioxidant and antimicrobial properties, but the functions are limited by its low aqueous solubility. To address this, two proteins, bovine serum albumin (BSA) and gelatin were used to form curcumin-protein nanocomplexes using a charge-switch method, by mixing oppositely charged curcumin and proteins. Complexation with BSA and gelatin increased the curcumin solubility to 391.77 (±15.70) μg mL

Identifiers

PMID40151536
PMCPMC11948305

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.