Evidence map›Paper›PMID 40151517›Full record

ArticlePalliative medicine reports2025

Effects of High-Resolution Natural Sound with Inaudible High-Frequency Components on Healing, Symptoms, and Sleep Satisfaction in Terminally Ill Cancer Patients.

Yasutaka Shimotsuura, Keisuke Ishizuka, Takashi Kawaguchi, Kazue Umetsu, Mariko Harada, Yujiro Inoue, Emi Kubo, Kazuhiro Kosugi, Takashi Igarashi, Seiya Enomoto and 5 more

Abstract read
In one paragraph

Article in Palliative medicine reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Yasutaka ShimotsuuraDepartment of Palliative Medicine, National Cancer Center Hospital East, Kashiwa, Japan.
Keisuke IshizukaDepartment of Palliative Medicine, National Cancer Center Hospital East, Kashiwa, Japan.
Takashi KawaguchiDepartment of Clinical Assessment, Tokyo University of Pharmacy and Life Sciences, Hachioji, Japan.
Kazue UmetsuDepartment of Palliative Medicine, National Cancer Center Hospital East, Kashiwa, Japan.
Mariko HaradaDepartment of Palliative Medicine, National Cancer Center Hospital East, Kashiwa, Japan.
Yujiro InoueDepartment of Palliative Medicine, National Cancer Center Hospital East, Kashiwa, Japan.
Emi KuboDepartment of Palliative Medicine, National Cancer Center Hospital East, Kashiwa, Japan.ORCID https://orcid.org/0000-0001-9369-2824
Kazuhiro KosugiDepartment of Palliative Medicine, National Cancer Center Hospital East, Kashiwa, Japan.
Takashi IgarashiDepartment of Pharmacy, National Cancer Center Hospital East, Kashiwa, Japan.
Seiya EnomotoJVCKENWOOD Corporation, Yokohama, Japan.
Hidehiko TaniyamaJVCKENWOOD Corporation, Yokohama, Japan.
Tetsuo IwataJVCKENWOOD Corporation, Yokohama, Japan.
Takuhiro YamaguchiDivision of Biostatistics, Tohoku University Graduate School of Medicine, Sendai, Japan.
Yoshihisa MatsumotoDepartment of Palliative Medicine, National Cancer Center Hospital East, Kashiwa, Japan.
Tomofumi MiuraDepartment of Palliative Medicine, National Cancer Center Hospital East, Kashiwa, Japan.ORCID https://orcid.org/0000-0002-7031-7279

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objectives: This study aimed to assess the effects of high-resolution natural sound with inaudible high-frequency components (HNIH) on healing, symptoms, sleep satisfaction, and autonomic nerve function among terminally ill cancer patients. Methods: We conducted a single-arm, open-label study of 4-hour HNIH for 20 terminally ill cancer patients. We evaluated the healing state, symptoms (Japanese version of the Edmonton Symptom Assessment System-Revised, ESAS-r-J), global impression, and heart rate variability at 30 minutes (T2) and 4 hours (T3) after starting HNIH and sleep satisfaction the next morning (T4). Results: A total of 18 participants were evaluated (mean age: 69.4 years; 33.3% female). Post-intervention, there was a nonsignificant increase in Healing Scale scores at T2 (mean difference: 5.3, 95% confidence interval [CI]: -1.2 to 11.8, Conclusions: The present single-arm study showed that HNIH potentially enhanced healing, alleviated symptoms such as anxiety, tiredness, and shortness of breath, and improved sleep satisfaction in terminally ill cancer patients.

Indexed as

cancerhealinghigh-resolution natural music with inaudible high-frequency componentsmusicpalliative care

Identifiers

PMID40151517
PMCPMC11947647

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.