ArticleReproductive medicine and biology
Serum copper to zinc ratio and risk of endometriosis: Insights from a case-control study in infertile patients.
Article in Reproductive medicine and biology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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Who cites it
4 citing papers in PubMed.
- Integrative gene ontology-driven analysis of the eutopic endometrium reveals key dysregulated functionomes and pathways in endometriosis.Journal of the Chinese Medical Association : JCMA · 2026Article
- Copper-Targeted Therapy in Experimental Endometriosis: Effects of Ammonium Tetrathiomolybdate on Markers of the Interconnected Processes of Inflammation, Innervation, and Fibrogenesis.International journal of molecular sciences · 2026Article
- The Role of Antioxidant Minerals in the Pathophysiology and Treatment of Endometriosis-Systematic Review.Antioxidants (Basel, Switzerland) · 2025Review
- Serum copper to zinc ratio and risk of endometriosis: Insights from a case-control study in infertile patients.Reproductive medicine and biologyArticle
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Authors and funding
4 authors.
Funding
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Abstract
Purpose: Endometriosis is a prevalent gynecological disorder, yet data on the role of trace metal elements in its risk remain limited. We aimed to investigate the relationship between serum copper (Cu), zinc (Zn), iron (Fe), magnesium (Mg) levels, and the Cu/Zn ratio with the risk of endometriosis. Methods: This study involved 568 infertile patients diagnosed with endometriosis, compared to 819 infertile patients without endometriosis (Control group). Basic characteristics, hormonal parameters, and essential trace elements of the patients were measured and analyzed. Results: The findings indicated a notable decrease in serum Zn levels in the endometriosis group compared to controls, alongside a significant increase in the Cu/Zn ratio ( Conclusions: This study provided evidence of decreased serum Zn levels and an increased Cu/Zn ratio being associated with an elevated risk of endometriosis among infertile patients. These findings offer valuable real-world data, enriching our understanding of endometriosis.
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