Evidence map›Paper›PMID 40151257›Full record

ArticleJACS Au2025

Electrochemical Synergistic Ni/Co-Catalyzed Carbonylative Cross-Electrophile Coupling of Aryl and Alkyl Halides with CO.

Shaokun Tao, Yun Yang, Li Chen, Jiaqi Xu, Haiyan Fu, Hua Chen, Weidong Jiang, Ruixiang Li, Weichao Xue, Xueli Zheng

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in JACS Au, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. An IntegratedACS catalysis · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Shaokun TaoKey Laboratory of Green Chemistry & Technology, Ministry of Education, College of Chemistry, Sichuan University, Chengdu, Sichuan 610064, P. R. China.
Yun YangKey Laboratory of Green Chemistry & Technology, Ministry of Education, College of Chemistry, Sichuan University, Chengdu, Sichuan 610064, P. R. China.
Li ChenKey Laboratory of Green Chemistry & Technology, Ministry of Education, College of Chemistry, Sichuan University, Chengdu, Sichuan 610064, P. R. China.
Jiaqi XuKey Laboratory of Green Chemistry & Technology, Ministry of Education, College of Chemistry, Sichuan University, Chengdu, Sichuan 610064, P. R. China.ORCID https://orcid.org/0000-0002-2774-5016
Haiyan FuKey Laboratory of Green Chemistry & Technology, Ministry of Education, College of Chemistry, Sichuan University, Chengdu, Sichuan 610064, P. R. China.ORCID https://orcid.org/0000-0002-7185-2062
Hua ChenKey Laboratory of Green Chemistry & Technology, Ministry of Education, College of Chemistry, Sichuan University, Chengdu, Sichuan 610064, P. R. China.ORCID https://orcid.org/0000-0003-4248-8019
Weidong JiangSchool of Chemistry and Environmental Engineering, Sichuan University of Science and Engineering, Zigong, Sichuan 643000, P. R. China.ORCID https://orcid.org/0000-0003-1775-6456
Ruixiang LiKey Laboratory of Green Chemistry & Technology, Ministry of Education, College of Chemistry, Sichuan University, Chengdu, Sichuan 610064, P. R. China.ORCID https://orcid.org/0000-0003-2358-1226
Weichao XueKey Laboratory of Green Chemistry & Technology, Ministry of Education, College of Chemistry, Sichuan University, Chengdu, Sichuan 610064, P. R. China.ORCID https://orcid.org/0000-0002-8376-9485
Xueli ZhengKey Laboratory of Green Chemistry & Technology, Ministry of Education, College of Chemistry, Sichuan University, Chengdu, Sichuan 610064, P. R. China.ORCID https://orcid.org/0000-0001-8394-0310

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Accessing unsymmetric ketones and achieving their carbon isotope labeling are crucial yet challenging tasks in both synthetic and medicinal chemistry. We report here an efficient electrochemical nickel-/cobalt-catalyzed carbonylative cross-electrophile coupling reaction. This method allows for the modular synthesis of a library of unsymmetric ketones from simple building blocks, including aryl halides, alkyl halides, and gaseous CO. The simultaneous use of nickel and cobalt salts as concerted catalysts ensures the high efficiency of this three-component carbonylative coupling. Furthermore, electrochemical reduction avoids the use of stoichiometric reductants, making this protocol more sustainable and attractive. The broad substrate scope and late-stage

Identifiers

PMID40151257
PMCPMC11937974

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.