Evidence map›Paper›PMID 40151122›Full record

ArticleJournal of traditional Chinese medicine = Chung i tsa chih ying wen pan2025

Effect of acupuncture on serum levels of hypothalamic-pituitary-adrenal axis related hormones and immune factors in rats with allergic rhinitis.

Kang Jiale, D U Zhongming, Guo Wei, D U Shuo, Han Guanxiong, Chen Sheng

Abstract read
In one paragraph

Article in Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Kang JialeDepartment of Acupuncture, Dongzhimen Hospital, Beijing University of Chinese Medicine, Beijing 100700, China.
D U ZhongmingDepartment of Acupuncture, Dongzhimen Hospital, Beijing University of Chinese Medicine, Beijing 100700, China.
Guo WeiDepartment of Traditional Chinese Medicine, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200011, China.
D U ShuoDepartment of Acupuncture, Dongzhimen Hospital, Beijing University of Chinese Medicine, Beijing 100700, China.
Han GuanxiongDepartment of Traditional Chinese Medicine, China Aerospace Science & Industry Corporation 731 Hospital, Beijing 100074, China.
Chen ShengDepartment of Acupuncture, Dongzhimen Hospital, Beijing University of Chinese Medicine, Beijing 100700, China.

Funding

National Natural Science Foundation of China: to Explore the Mechanism of Acupuncture Treatment on Rats with Allergic Rhinitis from the Hypothalamic-Pituitary-Adrenal (HPA) Axis and Serum Immune Factor Levels 82004455
6 · The paper itself

Abstract

objectiveTo explore the correlation between acupuncture treatment for allergic rhinitis (AR) and hypothalamic-pituitary-adrenal (HPA) axis regulation by investigating changes in serum immune factors, HPA axis-associated hormone levels, activation levels of paraventricular nucleus (PVN) neurons, and the severity of nasal mucosal lesions, in rats with AR before and after acupuncture treatment.

methodsAfter establishing the AR rat model, ovalbumin was administered

resultsFollowing the intervention period, the behavioral scores for the blank control group were lower than those of other groups (

conclusionAcupuncture can alleviate AR symptoms and regulate serum inflammatory factor levels and HPA axis-related hormones in AR rats. Moreover, these effects are inhibited by glucocorticoid antagonists, suggesting that acupuncture may regulate AR symptoms through HPA axis regulation.

Indexed as

Acupuncture TherapyHypothalamo-Hypophyseal SystemPituitary-Adrenal SystemRhinitis, AllergicAdrenocorticotropic HormoneAnimalsCorticosteroneCorticotropin-Releasing HormoneHumansInterferon-gammaMaleRatsRats, Sprague-DawleyAdrenocorticotropic HormoneCorticosteroneCorticotropin-Releasing HormoneInterferon-gammaacupunctureallergic rhinitisglucocorticoidshypothalamic-pituitary-adrenal axisimmunity

Identifiers

PMID40151122
PMCPMC11955754

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.