Evidence map›Paper›PMID 40150978›Full record

ArticleAdvanced materials (Deerfield Beach, Fla.)2025

Heterogeneous Nanopore Arrays - Selective Modification of Nanopores Embedded in a Membrane.

Ethan Cao, Zuzanna S Siwy

Abstract read
In one paragraph

Article in Advanced materials (Deerfield Beach, Fla.), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Ethan CaoDepartment of Physics and Astronomy, University of California, 210G Rowland Hall, Irvine, CA, 92697, USA.
Zuzanna S SiwyDepartment of Physics and Astronomy, University of California, 210G Rowland Hall, Irvine, CA, 92697, USA.ORCID https://orcid.org/0000-0003-2626-7873

Funding

National Science Foundation CHENational Science Foundation MPS 2200524National Science Foundation Major Research Instrumentation Program CHE-1338173Research Science and Engineering Center DMR-2011967
6 · The paper itself

Abstract

Much effort in the field of nanopore research has been directed toward reproducing the efficient transport phenomena of biological ion channels. For synthetic nanopores to replicate channel function on the scale of a cellular membrane, it is necessary to consider the modes of crosstalk between channels as well as to develop approaches to prepare nanopore arrays consisting of pores with different transport properties, akin to a membrane in an axon. In this manuscript, first ion concentration polarization (ICP) is identified as the primary means of the crosstalk, and subsequently, the extent and degree of ICP is tuned via targeted chemical modification of the pore walls' functional groups. Next, two fabrication methods of a model two-nanopore array are presented in a silicon nitride membrane in which one nanopore contains a bipolar ionic junction and functions as an ionic diode, while the other one is a homogeneously charged ionic resistor. The targeted chemical modification of a thin gold layer at the opening of one pore in an array that leaves the other pore located a few tens of nm away, unmodified, is utilized. These results provide an important framework for designing abiotic ionic circuits that can mimic physiological multichannel ion transport and communication.

Indexed as

concentration polarizationionic circuitsionic diodesnanopore arraytargeted chemical modification

Identifiers

PMID40150978
PMCPMC12721208

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.