Evidence map›Paper›PMID 40150883›Full record

ReviewExperimental physiology2025

Myths and methodologies: Invasive and non-invasive assessment of respiratory muscle activity in humans.

Anna L Hudson, Caroline J Jolley, Simon C Gandevia, Jane E Butler

Abstract readReview
In one paragraph

Review in Experimental physiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
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  4. Review
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  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Anna L HudsonFlinders Health and Medical Research Institute, Flinders University, Bedford Park, South Australia, Australia.ORCID https://orcid.org/0000-0002-0192-776X
Caroline J JolleyCentre for Human & Applied Physiological Sciences, School of Basic & Medical Biosciences, Faculty of Life Sciences & Medicine, King's College London, London, UK.
Simon C GandeviaNeuroscience Research Australia, Randwick, New South Wales, Australia.ORCID https://orcid.org/0000-0002-1345-3821
Jane E ButlerNeuroscience Research Australia, Randwick, New South Wales, Australia.

Funding

NHMRC
6 · The paper itself

Abstract

Survival relies on neural respiratory drive from the medullary respiratory centres to activate the respiratory muscles for breathing. Accurate assessment of respiratory muscle activity, as an estimate of neural respiratory drive in humans, will facilitate a greater understanding of respiratory physiology, the pathophysiology of diseases and injuries, clinical investigations and the neurophysiology of breathlessness perception. Here, we highlight the methodologies to measure respiratory muscle activity, their appropriate application, the potential limitations of the data and their safety and feasibility considerations. These recommendations can be applied to all skeletal muscles.

Indexed as

Respiratory MusclesElectromyographyHumansdiaphragmelectromyographyintercostal musclesingle motor unit

Identifiers

PMID40150883
PMCPMC12314637

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.