ArticleBioengineering (Basel, Switzerland)2025
Can the Novel Photon-Counting CT Scan Accurately Predict Aortic Wall Thickness? Preliminary Results.
Article in Bioengineering (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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1 citing paper in PubMed.
- A scoping review of photon-counting detector computed tomography in cardiovascular imaging.Diagnostic and interventional radiology (Ankara, Turkey) · 2026Article
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11 authors.
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Abstract
backgroundSurgical indication of ascending thoracic aortic aneurysms (ATAA) is generally performed in prevention. Guidelines use aortic diameter as a predictor of rupture and dissection; however, this single parameter alone has a limited value in predicting the real-world risk of acute aortic syndromes. The novel photon-counting CT scan(pc-CT) is capable of better-analyzing tissue composition and aortic characterization. The aim of the study is to assess whether the correlation between aortic wall thickness measured with a pc-CT scan and histology exists.
methods14 Patients, with a mean age of 47 years, undergoing cardiac surgery for ATAA, who had preoperatively undergone a pc-CT scan, were retrospectively analyzed. Histology analyses of the resected aortic wall aneurysm were reviewed, and minimum/maximum measurements of intima+media of the aortic wall were performed. Radiology images were also examined, and aortic wall thickness measures were taken. Bland-Altman plots and Passing-Bablock regression analyses were conducted to evaluate the correlation between the values.
resultspc-CT scan mean measurements were 1.05 and 1.69 mm, minimum/maximum, respectively. Mean minimum/maximum histology measurements were 1.66 and 2.82 mm, respectively. Bland Altman plots and Passing-Bablock regression analyses showed the absence of systematic bias and confirmed that measurement values were sufficiently similar (minimum -0.61 [CI 95% 0.16-1.38]; maximum -1.1 [0.73-2.99]).
conclusionsDespite results being merely preliminary, our study shows encouraging sufficiently similar results between aortic wall thickness measurements made with pc-CT scan and histology analyses.
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