Evidence map›Paper›PMID 40150725›Full record

ArticleBioengineering (Basel, Switzerland)2025

Third Body Wear of an All-Polymer, PEEK-OPTIMA™ on Ultra-High-Molecular-Weight Polyethylene Total Knee Replacement.

Raelene M Cowie, Jens Schwiesau, Thomas M Grupp, Adam Briscoe, Louise M Jennings

Abstract read
In one paragraph

Article in Bioengineering (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Raelene M CowieInstitute of Medical and Biological Engineering, University of Leeds, Leeds LS2 9JT, UK.ORCID 0000-0003-3903-5916
Jens SchwiesauResearch & Development, Aesculap AG, 78532 Tuttlingen, Germany.ORCID 0000-0001-6581-3238
Thomas M GruppResearch & Development, Aesculap AG, 78532 Tuttlingen, Germany.ORCID 0000-0002-1068-7497
Adam BriscoeInstitute of Medical and Biological Engineering, University of Leeds, Leeds LS2 9JT, UK.
Louise M JenningsInstitute of Medical and Biological Engineering, University of Leeds, Leeds LS2 9JT, UK.ORCID 0000-0003-1446-4511

Funding

EPSRC EP/N00941X/1Invibio Knees Ltd N/A
6 · The paper itself

Abstract

Experimental wear simulation of a PEEK-OPTIMA™ polymer-on-UHMWPE total knee replacement has shown equivalent UHMWPE wear to conventional knee replacement materials (cobalt chrome-on-UHMWPE) when tested in a clean environment. The aim of this study was to experimentally investigate the wear of this all-polymer total knee replacement under third body wear conditions. Three PEEK-OPTIMA™ and three cobalt chrome femoral components articulating against all-polyethylene tibial components were tested in a knee simulator. One million cycles of wear simulation was carried out in clean lubricant under conditions replicating walking followed by one million cycles with the lubricant contaminated with porcine bone particles, then one million cycles with PMMA cement particles. UHMWPE wear was determined gravimetrically. Statistical analysis compared UHMWPE wear against PEEK femoral components to cobalt chrome. In clean lubricant and with bone particles in the lubricant, there was no significant difference (

Indexed as

experimental simulationkneePEEK-OPTIMAthird body wearUHMWPE

Identifiers

PMID40150725
PMCPMC11939626

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.