Evidence map›Paper›PMID 40150547›Full record

ArticleChildren (Basel, Switzerland)2025

Sustained Reduction in Severe Intraventricular Hemorrhage in Micropremature Infants: A Quality Improvement Intervention.

Sabrina E Wong, Lisa Sampson, Michael Dunn, Asaph Rolnitsky, Eugene Ng

Abstract read
In one paragraph

Article in Children (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Sabrina E WongSunnybrook Health Sciences Centre, Toronto, ON M4N 3M5, Canada.
Lisa SampsonSunnybrook Health Sciences Centre, Toronto, ON M4N 3M5, Canada.
Michael DunnSunnybrook Health Sciences Centre, Toronto, ON M4N 3M5, Canada.ORCID 0000-0002-3908-4147
Asaph RolnitskySunnybrook Health Sciences Centre, Toronto, ON M4N 3M5, Canada.ORCID 0000-0002-3399-0130
Eugene NgSunnybrook Health Sciences Centre, Toronto, ON M4N 3M5, Canada.ORCID 0000-0003-4329-8401

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundQuality improvement (QI) interventions may reduce the incidence and severity of Intraventricular Hemorrhage (IVH) in the population of inborn micropremature infants (born at ≤26 weeks' gestation) with the goal of improving outcomes in this high-risk population.

methodsA multidisciplinary team reviewed the current literature to develop a site-specific brain protective bundle. Baseline data were collected from June 2014 to February 2015, with interventions occurring from March 2015 to December 2015. The period of sustainability was assessed from January 2016 to December 2023. Control charts were used to analyze the effect of the interventions. Outcome measures included all grades of IVH, periventricular leukomalacia (PVL), necrotizing enterocolitis (NEC), and spontaneous intestinal perforations (SIP).

resultsBrain care initiatives decrease the rate of severe IVH in the inborn micropremature infant population from a baseline of 21% to 6.45% with a sustained rate of 4.5% with no change to balancing measures.

conclusionsBrain-protective initiatives such as midline head positioning and minimal handling are associated with a significant and sustained reduction in severe IVH among inborn micropremature infants.

Indexed as

brain injuryintraventricular hemorrhageprematurity

Identifiers

PMID40150547
PMCPMC11941624

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.