Evidence map›Paper›PMID 40150497›Full record

ArticleHealthcare (Basel, Switzerland)2025

ChatGPT-4o and 4o1 Preview as Dietary Support Tools in a Real-World Medicated Obesity Program: A Prospective Comparative Analysis.

Louis Talay, Leif Lagesen, Adela Yip, Matt Vickers, Neera Ahuja

Abstract read
In one paragraph

Article in Healthcare (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Louis TalayFaculty of Arts and Social Sciences, University of Sydney, Sydney, NSW 2050, Australia.ORCID 0000-0002-5390-8392
Leif LagesenDietitians Australia, Phillip, ACT 2606, Australia.
Adela YipHarvard T.H. Chan School of Public Health, Harvard University, Boston, MA 02115, USA.
Matt VickersEucalyptus, Sydney, NSW 2000, Australia.
Neera AhujaHospital Medicine Division, Department of Medicine, Stanford University, Stanford, CA 94305, USA.ORCID 0000-0002-2979-7530

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND/

objectivesClinicians are becoming increasingly interested in the use of large language models (LLMs) in obesity services. While most experts agree that LLM integration would increase access to obesity care and its efficiency, many remain skeptical of their scientific accuracy and capacity to convey human empathy. Recent studies have shown that ChatGPT-3 models are capable of emulating human dietitian responses to a range of basic dietary questions.

methodsThis study compared responses of two ChatGPT-4o models to those from human dietitians across 10 complex questions (5 broad; 5 narrow) derived from patient-clinician interactions within a real-world medicated digital weight loss service.

resultsInvestigators found that neither ChatGPT-4o nor Chat GPT-4o1 preview were statistically outperformed (

conclusionsThese results provide preliminary evidence that advanced LLMs may be able to play a significant supporting role in medicated obesity services. Research in other obesity contexts is needed before any stronger conclusions are made about LLM lifestyle coaching and whether such initiatives increase care access.

Indexed as

ChatGPT-4odieteticsdigital weight loss serviceshealth coachingweight loss medications

Identifiers

PMID40150497
PMCPMC11942132

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.