Evidence map›Paper›PMID 40150374›Full record

ArticleAnimals : an open access journal from MDPI2025

Theaflavin Reduces Oxidative Stress and Apoptosis in Oxidized Protein-Induced Granulosa Cells and Improves Production Performance in Laying Hens.

Ling Zhou, Li Lv, Pinyao Zhao, Jinwei Zhang, Yan Liu, Wei Zhao, Keying Zhang, Shuwen Du

Abstract read
In one paragraph

Article in Animals : an open access journal from MDPI, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Effect of DietaryVeterinary sciences · 2026
    Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Ling ZhouDepartment of Quality Management and Inspection & Quarantine, Yibin University, Yibin 644001, China.
Li LvInstitute of Brain Science and Diseases, West China Hospital of Sichuan University, Chengdu 610041, China.ORCID 0000-0002-4386-287X
Pinyao ZhaoDepartment of Quality Management and Inspection & Quarantine, Yibin University, Yibin 644001, China.
Jinwei ZhangDepartment of Quality Management and Inspection & Quarantine, Yibin University, Yibin 644001, China.
Yan LiuDepartment of Quality Management and Inspection & Quarantine, Yibin University, Yibin 644001, China.
Wei ZhaoDepartment of Quality Management and Inspection & Quarantine, Yibin University, Yibin 644001, China.
Keying ZhangInstitute of Animal Nutrition, Key Laboratory for Animal Disease-Resistance Nutrition of China Ministry of Education, Sichuan Agricultural University, Chengdu 611134, China.ORCID 0000-0002-2909-3357
Shuwen DuDepartment of Quality Management and Inspection & Quarantine, Yibin University, Yibin 644001, China.

Funding

Research Project of Yibin university 2022QH04Youths Fund of Natural Science Foundation in Sichuan Province 2023NSFSC1137
6 · The paper itself

Abstract

This study aims to investigate the effects of theaflavins on production performance and egg quality in laying hens fed oxidized corn gluten meal while evaluating their antioxidant and anti-apoptotic effects on granulosa cells (GCs) from chicken follicles. In total, 600 Lohmann commercial laying hens, aged 64 weeks, were randomly assigned to four treatment groups: a control group, a theaflavin-supplemented group, an oxidized corn gluten meal group, and a combination group. After 8 weeks of feeding, production performance, egg quality, and antioxidant status, along with GC apoptosis and the antioxidant capacity of eggs, were measured. The results demonstrated that oxidized corn gluten meal significantly reduced production performance, antioxidant capacity, and egg quality in laying hens while increasing GC apoptosis. Theaflavin significantly enhanced egg production during weeks 5-8, along with superoxide dismutase activity in the liver, serum, and ovary, alongside egg white reducing power and egg yolk threonine content (

Indexed as

granulosa cellslaying hensoxidized corn gluten mealproduction performancetheaflavin

Identifiers

PMID40150374
PMCPMC11939771

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.