Evidence map›Paper›PMID 40150351›Full record

ArticleAnimals : an open access journal from MDPI2025

Aspirin Eugenol Ester Modulates the Hypothalamus Transcriptome in Broilers Under High Stocking Density.

Xiaodie Zhao, Yi Zhang, Dongying Bai, Wenrui Zhen, Caifang Guo, Ziwei Wang, Penghui Ma, Xiqiang Ma, Xiaolin Xie, Koichi Ito and 4 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Animals : an open access journal from MDPI, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Xiaodie ZhaoDepartment of Animal Physiology, College of Animal Science and Technology, Henan University of Science and Technology, Luoyang 471003, China.
Yi ZhangDepartment of Animal Physiology, College of Animal Science and Technology, Henan University of Science and Technology, Luoyang 471003, China.ORCID 0000-0002-4773-287X
Dongying BaiDepartment of Animal Physiology, College of Animal Science and Technology, Henan University of Science and Technology, Luoyang 471003, China.
Wenrui ZhenDepartment of Animal Physiology, College of Animal Science and Technology, Henan University of Science and Technology, Luoyang 471003, China.ORCID 0000-0002-3433-8398
Caifang GuoDepartment of Animal Physiology, College of Animal Science and Technology, Henan University of Science and Technology, Luoyang 471003, China.
Ziwei WangDepartment of Animal Physiology, College of Animal Science and Technology, Henan University of Science and Technology, Luoyang 471003, China.
Penghui MaDepartment of Animal Physiology, College of Animal Science and Technology, Henan University of Science and Technology, Luoyang 471003, China.
Xiqiang MaInnovative Research Team of Livestock Intelligent Breeding and Equipment, Science & Technology Innovation Center for Completed Set Equipment, Longmen Laboratory, Luoyang 471023, China.ORCID 0000-0001-8933-4557
Xiaolin XieInnovative Research Team of Livestock Intelligent Breeding and Equipment, Science & Technology Innovation Center for Completed Set Equipment, Longmen Laboratory, Luoyang 471023, China.
Koichi ItoDepartment of Food and Physiological Models, Graduate School of Agricultural and Life Sciences, The University of Tokyo, Tsukuba 319-0206, Japan.
Bingkun ZhangState Key Laboratory of Animal Nutrition, Department of Animal Nutrition and Feed Science, College of Animal Science and Technology, China Agricultural University, Beijing 100193, China.
Yajun YangKey Lab of New Animal Drug of Gansu Province, Key Lab of Veterinary Pharmaceutical Development of Ministry of Agriculture and Rural Affairs, Lanzhou Institute of Husbandry and Pharmaceutical Science of Chinese Academy of Agricultural Sciences, Lanzhou 730046, China.
Jianyong LiKey Lab of New Animal Drug of Gansu Province, Key Lab of Veterinary Pharmaceutical Development of Ministry of Agriculture and Rural Affairs, Lanzhou Institute of Husbandry and Pharmaceutical Science of Chinese Academy of Agricultural Sciences, Lanzhou 730046, China.ORCID 0000-0003-3317-0666
Yanbo MaDepartment of Animal Physiology, College of Animal Science and Technology, Henan University of Science and Technology, Luoyang 471003, China.

Funding

Frontier Exploration Projects of Longmen Laboratory LMQYTSKT037Key Research and Development and Promotion of Special (Science and Technology) Project of Henan Province 242102110018Key Research and Development Program of Henan Province 241111113800Key Scientific Research Foundation of the Higher Education Institutions of Henan Province 22A230001National Key Research and Development Program of China 2022YFE0111100Program for International S&T Cooperation Projects of Henan 232102521012Trendy Industry Projects of Longmen Laboratory LMFKCY2023002
6 · The paper itself

Abstract

Broilers grown in a high-density (HD) stocking environment may experience intense competition that may adversely affect their growth relative to animals reared at a normal density (ND). The growth performance of HD broilers is increased by aspirin eugenol ester (AEE), although the mechanism by which this compound modulates hypothalamus-regulated feeding behavior is unclear. The aims of this study were to determine the effects of including AEE in the basal diet on the hypothalamic transcriptome and to examine in parallel the impact of these modifications on broiler production performance in HD conditions. Three hundred sixty one-day-old male Arbor Acres broilers were randomly divided into four groups: an ND group (14 broilers/m

Indexed as

aspirin eugenol esterbroilerhigh stocking densityhypothalamusRNA-seqtranscriptome

Identifiers

PMID40150351
PMCPMC11939338

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.