Evidence map›Paper›PMID 40150332›Full record

ArticleAnimals : an open access journal from MDPI2025

Immunological Responses and Protection in the Largemouth Bass (

Tao Yang, Jiale Zhai, Chenyang Li, Lingbing Zeng, Yiqun Li, Wenzhi Liu, Yan Meng, Yuding Fan, Zhenyu Huang, Yong Zhou and 1 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Animals : an open access journal from MDPI, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Outer membrane vesicles fromMicrobiology spectrum · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Tao YangDepartment of Aquatic Animal Medicine, College of Fisheries, Huazhong Agricultural University, Wuhan 430070, China.
Jiale ZhaiDepartment of Aquatic Animal Medicine, College of Fisheries, Huazhong Agricultural University, Wuhan 430070, China.
Chenyang LiTongwei Agricultural Development Co., Ltd., Tongwei Co., Ltd., Chengdu 610041, China.
Lingbing ZengDepartment of Aquatic Animal Medicine, College of Fisheries, Huazhong Agricultural University, Wuhan 430070, China.ORCID 0000-0001-7196-0955
Yiqun LiDivision of Fish Disease, Yangtze River Fisheries Research Institute, Chinese Academy of Fishery Sciences, Wuhan 430223, China.
Wenzhi LiuDivision of Fish Disease, Yangtze River Fisheries Research Institute, Chinese Academy of Fishery Sciences, Wuhan 430223, China.
Yan MengDivision of Fish Disease, Yangtze River Fisheries Research Institute, Chinese Academy of Fishery Sciences, Wuhan 430223, China.ORCID 0000-0002-8846-2191
Yuding FanDivision of Fish Disease, Yangtze River Fisheries Research Institute, Chinese Academy of Fishery Sciences, Wuhan 430223, China.ORCID 0000-0002-7291-2493
Zhenyu HuangDivision of Fish Disease, Yangtze River Fisheries Research Institute, Chinese Academy of Fishery Sciences, Wuhan 430223, China.
Yong ZhouDepartment of Aquatic Animal Medicine, College of Fisheries, Huazhong Agricultural University, Wuhan 430070, China.ORCID 0000-0003-0373-5734
Nan JiangDivision of Fish Disease, Yangtze River Fisheries Research Institute, Chinese Academy of Fishery Sciences, Wuhan 430223, China.

Funding

the Central Public-interest Scientific Institution Basal Research Fund 2023TD46the Central Public-interest Scientific Institution Basal Research Fund YFI202416the China Postdoctoral Science Foundation 2024M763655the Chongqing Aquatic Science and Technology Innovation Alliance CQFTIU202504-1the Hubei Provincial Natural Science Foundation of China 2024AFB251the National Key Research and Development Program of China 2023YFD2400704the National Natural Science Foundation of China 32202980the Research and Demonstration of Key Technologies for Healthy Aquaculture of Largemouth Bass 2022YFN0012the Science and Technology Innovation Yongjiang 2035 Key Research and Development Project of Ningbo 2024Z279the Xinjiang Uygur Autonomous Region key research and development task special 2024B02014-2
6 · The paper itself

Abstract

The largemouth bass ranavirus (LMBRaV) caused significant mortality and economic loss in the largemouth bass aquaculture industry around the world, including China. Vaccination is an efficient method for virus defense. In this study, an inactivated LMBRaV vaccine was prepared, and the prevention effect as well as the immune responses were analyzed after the primary and the secondary immunization. Compared to the control group, the counts of leucocytes and erythrocytes increased and peaked at day 14 after the primary immunization, and the proportions of leucocytes, including lymphocytes, monocytes, and neutrophils, were also up-regulation after the primary immunization. Serum neutralizing antibody titers increased and peaked (1:128) at day 28 after the primary immunization. Following the secondary immunization, antibody titers were increased to a higher level (1:512) at 28 days after the secondary immunization. Quantitative real-time PCR analysis demonstrated varying degrees of up-regulation of

Indexed as

immune responseinactivated vaccinelargemouth basslargemouth bass ranavirusrelative percent survival rates

Identifiers

PMID40150332
PMCPMC11939246

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.