Evidence map›Paper›PMID 40150307›Full record

ArticleAnimals : an open access journal from MDPI2025

Whole-Genome Sequencing-Based Population Genetic Analysis of Wild and Domestic Rabbit Breeds.

Zsófia Fekete, Zoltán Német, Nóra Ninausz, Péter Fehér, Mátyás Schiller, Maher Alnajjar, Áron Szenes, Tibor Nagy, Viktor Stéger, Levente Kontra and 1 more

Abstract read
In one paragraph

Article in Animals : an open access journal from MDPI, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Zsófia FeketeDepartment of Genetics and Genomics, Institute of Genetics and Biotechnology, Hungarian University of Agriculture and Life Sciences, Szent-Györgyi A. u. 4, H-2100 Gödöllő, Hungary.ORCID 0000-0002-9086-5459
Zoltán NémetDepartment of Pathology, University of Veterinary Medicine Budapest, Dóra major, H-2225 Üllő, Hungary.ORCID 0000-0002-2044-1554
Nóra NinauszDepartment of Genetics and Genomics, Institute of Genetics and Biotechnology, Hungarian University of Agriculture and Life Sciences, Szent-Györgyi A. u. 4, H-2100 Gödöllő, Hungary.
Péter FehérDepartment of Genetics and Genomics, Institute of Genetics and Biotechnology, Hungarian University of Agriculture and Life Sciences, Szent-Györgyi A. u. 4, H-2100 Gödöllő, Hungary.
Mátyás SchillerDepartment of Genetics and Genomics, Institute of Genetics and Biotechnology, Hungarian University of Agriculture and Life Sciences, Szent-Györgyi A. u. 4, H-2100 Gödöllő, Hungary.
Maher AlnajjarDepartment of Genetics and Genomics, Institute of Genetics and Biotechnology, Hungarian University of Agriculture and Life Sciences, Szent-Györgyi A. u. 4, H-2100 Gödöllő, Hungary.ORCID 0000-0003-3613-3510
Áron SzenesDepartment of Pathology, University of Veterinary Medicine Budapest, Dóra major, H-2225 Üllő, Hungary.
Tibor NagyDepartment of Genetics and Genomics, Institute of Genetics and Biotechnology, Hungarian University of Agriculture and Life Sciences, Szent-Györgyi A. u. 4, H-2100 Gödöllő, Hungary.ORCID 0000-0002-4451-0796
Viktor StégerDepartment of Genetics and Genomics, Institute of Genetics and Biotechnology, Hungarian University of Agriculture and Life Sciences, Szent-Györgyi A. u. 4, H-2100 Gödöllő, Hungary.
Levente KontraDepartment of Genetics and Genomics, Institute of Genetics and Biotechnology, Hungarian University of Agriculture and Life Sciences, Szent-Györgyi A. u. 4, H-2100 Gödöllő, Hungary.ORCID 0000-0001-7518-7533
Endre BartaDepartment of Genetics and Genomics, Institute of Genetics and Biotechnology, Hungarian University of Agriculture and Life Sciences, Szent-Györgyi A. u. 4, H-2100 Gödöllő, Hungary.ORCID 0000-0002-6753-0714

Funding

Ministry of Culture and Innovation of Hungary from the National Research, Development and Innovation Fund TKP2021-NKTA-34National Research, Development and Innovation Office 2017-1.3.1-VKE-2017-00026National Research, Development and Innovation Office OTKA K 132814
6 · The paper itself

Abstract

The European rabbit exists in the wild and has several highly bred domesticated forms. There are well-separated wild European rabbit populations, and intensive breeding has resulted in various forms and utilizations. In this work, we aimed to carry out an extended WGS-based population genomics study on several wild European rabbit populations and selected breeds. Utilizing multiple methods, we showed that although domestic and wild populations were clearly separated, there was evidence of admixture between them in France and Hungary. The populations showed various levels of inbreeding, with one of the Hungarian subpopulations having excess runs of homozygosity. We identified numerous variants fixed in either domestic or wild animals, two of which were found to be fixed at different alleles in the two populations. Some putatively selected regions did not overlap with any known genes in the rabbit genome, suggesting some importance to these intergenic sites. The enrichment of selected regions in certain types of transcription factor binding sites suggests a possible role for these regulatory elements during domestication. In addition, the new high-coverage rabbit whole-genome sequences may provide helpful material for further population genetics analyses.

Indexed as

breedingdomesticationpopulation geneticspopulation genomicsrabbit

Identifiers

PMID40150307
PMCPMC11939179

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.