Evidence map›Paper›PMID 40149849›Full record

ReviewBiomolecules2025

Quercetin: Molecular Insights into Its Biological Roles.

Hye Joon Boo, Danbi Yoon, Yujeong Choi, Younghyun Kim, Jeong Seok Cha, Jiho Yoo

Abstract readReview
In one paragraph

Review in Biomolecules, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Review
  5. Food-grade TiOJournal of nanobiotechnology · 2026
    Article
  6. Review
  7. Review
  8. Article
  9. Advances in quercetin-based therapeutics for breast cancer: natural, synthetic, and nanotechnology-driven approaches.Medicinal chemistry research : an international journal for rapid communications on design and mechanisms of action of biologically active agents · 2026
    Review
  10. Review
  11. Benzofuran compound fromFrontiers in pharmacology · 2026
    Article
  12. Article
  13. Article
  14. Article
  15. Review
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Hye Joon BooCollege of Pharmacy, Chung-Ang University, Seoul 06974, Republic of Korea.
Danbi YoonCollege of Pharmacy, Chung-Ang University, Seoul 06974, Republic of Korea.
Yujeong ChoiCollege of Pharmacy, Chung-Ang University, Seoul 06974, Republic of Korea.
Younghyun KimCollege of Pharmacy, Chung-Ang University, Seoul 06974, Republic of Korea.
Jeong Seok ChaResearch Institute of Pharmacy, Chung-Ang University, Seoul 06974, Republic of Korea.ORCID 0000-0001-7856-1236
Jiho YooCollege of Pharmacy, Chung-Ang University, Seoul 06974, Republic of Korea.ORCID 0000-0002-0864-2142

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Quercetin, a prevalent plant flavonoid, demonstrates many biological functions through its interaction with distinct protein targets. Recent structural investigations of protein-quercetin complexes have elucidated the molecular mechanism behind these actions. This paper presents a thorough structural analysis of experimentally established protein-quercetin complex structures published to date. The structure of the protein-quercetin complex elucidates the molecular mechanism by which quercetin influences protein function. These structures illustrate how quercetin's chemical characteristics facilitate diverse modes of action by enabling particular interactions with the target protein. This structural knowledge provides the molecular foundation for comprehending quercetin's biological roles and indicates avenues for future structural investigations of flavonoid-protein complexes, especially those with ambiguous molecular processes.

Indexed as

ProteinsQuercetinHumansProtein BindingProteinsQuercetinflavonoidmolecular mechanismprotein structurequercetinstructural biologyX-ray crystallography

Identifiers

PMID40149849
PMCPMC11940409

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.