Evidence map›Paper›PMID 40149824›Full record

ArticleBrain sciences2025

Infarct Growth Rate Predicts Early Neurological Improvement in Ischemic Stroke After Endovascular Thrombectomy.

Zhihang Huang, Shuaiyu Chen, Bin Wei, Yan E, Jingwen Qi, Xiaohao Zhang, Teng Jiang

Abstract read
In one paragraph

Article in Brain sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Zhihang HuangDepartment of Neurology, Nanjing First Hospital, Nanjing Medical University, Nanjing 210006, China.
Shuaiyu ChenDepartment of Neurology, Nanjing First Hospital, Nanjing Medical University, Nanjing 210006, China.
Bin WeiDepartment of Neurology, Nanjing First Hospital, Nanjing Medical University, Nanjing 210006, China.
Yan EDepartment of Neurology, Nanjing First Hospital, Nanjing Medical University, Nanjing 210006, China.
Jingwen QiDepartment of Neurology, Nanjing First Hospital, Nanjing Medical University, Nanjing 210006, China.
Xiaohao ZhangDepartment of Neurology, Nanjing First Hospital, Nanjing Medical University, Nanjing 210006, China.
Teng JiangDepartment of Neurology, Nanjing First Hospital, Nanjing Medical University, Nanjing 210006, China.ORCID 0000-0003-4170-1156

Funding

China Postdoctoral Science Foundation 2023M731746Nanjing Medical Science and Technology Development Foundation YKK23111Nanjing Medical Science and Technology Development Foundation for Distinguished Young Scholars JQX23006National Natural Science Foundation of China 82371311
6 · The paper itself

Abstract

background and purposeThe infarct growth rate (IGR) is a major modifier of the therapeutic effect of endovascular thrombectomy. The objective of this paper was to explore the utility of the IGR measured by perfusion the imaging in predicting early neurological improvement (ENI) of patients treated with EVT.

methodsWe reviewed consecutive large vessel occlusive stroke in the anterior circulation and treated by thrombectomy between October 2019 to July 2024. The IGR was defined as the ischemic core volume (apparent diffusion coefficient ≤ 620 × 10

resultsA total of 407 patients (mean age, 69.3 ± 12.5 years; 63.1% of male) were included, of whom 149 (36.6%) achieved ENI. Among all enrolled patients, 281 patients were classified as slow (IGR < 10 mL/h) and 126 fast progressors (IGR ≥ 10 mL/h). In multivariable analyses, fast progressors had a lower likelihood of achieving ENI after endovascular thrombectomy (odds ratio, 0.442; 95% confidence intervals, 0.269-0.729,

conclusionsThe present study found that the pre-treatment IGR was associated with ENI in thrombectomy patients.

Indexed as

IGRlarge vessel occlusionmechanical thrombectomyneurological improvement

Identifiers

PMID40149824
PMCPMC11940323

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.