ReviewBrain sciences2025
Hypoglossal Nerve Palsy Following Cervical Spine Surgery-Two Case Reports and a Systematic Review of the Literature.
Review in Brain sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.
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Who cites it
3 citing papers in PubMed, 1 synthesis or guideline pooled it.
- The impact of surgical laterality on recurrent laryngeal nerve palsy in anterior cervical discectomy and fusion: A meta-analysis.Neurosurgical review · 2025Pooled it
- Nerve injuries in cervical spine surgery via anterior approach: a comprehensive review.Journal of spine surgery (Hong Kong) · 2025Review
- C2-C3 anterior cervical discectomy: Anatomical considerations and outcomes.Journal of craniovertebral junction & spineArticle
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Authors and funding
5 authors.
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No grant is acknowledged in the PubMed record.
Abstract
BACKGROUND/
objectivesHypoglossal nerve palsy (HNP) is a rare complication after cervical spine surgery and is reported after both anterior and posterior approaches. It often presents with dysarthria, dysphagia, and hoarseness. We present a systematic review of the literature and two cases of patients presenting with confirmed HNP after anterior cervical spine surgery.
methodsTwo retrospective case reports and a systematic review of the literature were presented. The electronic databases PubMed and Web of Science were systematically searched from inception.
resultsIn total, 17 cases of HNP were reported in the literature, including the two hereby presented. Ten cases involved the anterior approach and seven the posterior approach. The reported risk of HNP following cervical spine surgery varied between 0.01% and 2.5% depending on the procedure. The main etiology was mechanical compression of the nerve. Most of the cases recovered within a few months with conservative treatment. In some cases, permanent hypoglossal injury with persistent symptoms was reported. In both of the current cases, the symptoms gradually improved and completely resolved after a few months.
conclusionsHNP is a rare complication after cervical spine surgery. The causes of hypoglossal palsy are multifactorial, but mechanical injury is the most common. A thorough understanding of the nerve's anatomy is essential to minimize the risk of injury during anesthesia, patient positioning, and surgery. Understanding the underlying mechanisms contributing to HNP post-cervical spine surgery enables the implementation of preventive measures to mitigate its occurrence.
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