Evidence map›Paper›PMID 40149708›Full record

ReviewBiomedicines2025

Beyond Bone Remodeling: Denosumab's Multisystemic Benefits in Musculoskeletal Health, Metabolism, and Age-Related Diseases-A Narrative Review.

Yi-Ting Hung, Wen-Tien Wu, Ru-Ping Lee, Ting-Kuo Yao, Kuang-Ting Yeh

Abstract readReview
In one paragraph

Review in Biomedicines, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Bone Health in Rheumatoid Arthritis: An Update.Current rheumatology reports · 2026
    Review
  2. Review
  3. Bone and Infections: An Osteoimmunological Interplay.International journal of molecular sciences · 2026
    Review
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Yi-Ting HungSchool of Medicine, Tzu Chi University, Hualien 970374, Taiwan.
Wen-Tien WuSchool of Medicine, Tzu Chi University, Hualien 970374, Taiwan.ORCID 0000-0001-6945-712X
Ru-Ping LeeInstitute of Medical Sciences, Tzu Chi University, Hualien 970374, Taiwan.ORCID 0000-0001-6624-5893
Ting-Kuo YaoDepartment of Orthopedics, Hualien Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, Hualien 970473, Taiwan.
Kuang-Ting YehSchool of Medicine, Tzu Chi University, Hualien 970374, Taiwan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

osteoporosisosteosarcopenia denosumabRANKL inhibitorRANK/RANKL/OPG pathway (RRO pathway)sarcopenia

Identifiers

PMID40149708
PMCPMC11940544

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.