Evidence map›Paper›PMID 40149582›Full record

ArticleBiomedicines2025

A2-Astrocyte Activation by Short-Term Hypoxia Rescues α-Synuclein Pre-Formed-Fibril-Induced Neuronal Cell Death.

Ha Nyeoung Choi, Seon-Hee Kim, Min Gi Jo, Bina Lee, Young Jin Kim, So Eun Lee, Jeong Hyun Lee, Hye Min Seong, Seong Jae Kim, Sang Won Park and 6 more

Abstract read
In one paragraph

Article in Biomedicines, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Ha Nyeoung ChoiDepartment of Pharmacology, Institute of Medical Science, College of Medicine, Gyeongsang National University, Jinju 52727, Republic of Korea.
Seon-Hee KimDepartment of Pharmacology, Institute of Medical Science, College of Medicine, Gyeongsang National University, Jinju 52727, Republic of Korea.ORCID 0000-0003-1099-1728
Min Gi JoDepartment of Pathology, College of Medicine, Kyung Hee University, Seoul 02447, Republic of Korea.
Bina LeeDepartment of Pharmacology, Institute of Medical Science, College of Medicine, Gyeongsang National University, Jinju 52727, Republic of Korea.
Young Jin KimDepartment of Pharmacology, Institute of Medical Science, College of Medicine, Gyeongsang National University, Jinju 52727, Republic of Korea.
So Eun LeeDepartment of Pharmacology, Institute of Medical Science, College of Medicine, Gyeongsang National University, Jinju 52727, Republic of Korea.
Jeong Hyun LeeDepartment of Pharmacology, Institute of Medical Science, College of Medicine, Gyeongsang National University, Jinju 52727, Republic of Korea.
Hye Min SeongDepartment of Ophthalmology, Institute of Health Sciences, College of Medicine, Gyeongsang National University, Jinju 52727, Republic of Korea.ORCID 0000-0003-0952-8197
Seong Jae KimDepartment of Ophthalmology, Institute of Health Sciences, College of Medicine, Gyeongsang National University, Jinju 52727, Republic of Korea.ORCID 0000-0002-4143-3959
Sang Won ParkDepartment of Pharmacology, Institute of Medical Science, College of Medicine, Gyeongsang National University, Jinju 52727, Republic of Korea.ORCID 0000-0002-6149-5284
Hye Jung KimDepartment of Pharmacology, Institute of Medical Science, College of Medicine, Gyeongsang National University, Jinju 52727, Republic of Korea.ORCID 0000-0002-7067-6810
Heeyoung KangDepartment of Neurology, Gyeongsang National University Hospital, Jinju 52727, Republic of Korea.ORCID 0000-0001-5404-1674
Chan Hyun LeeDepartment of Neurology, Gyeongsang National University Hospital, Jinju 52727, Republic of Korea.ORCID 0000-0003-0330-175X
Min Young LeeCollege of Pharmacy, Research Institute of Pharmaceutical Sciences, Vessel-Organ Interaction Research Center (VOICE, MRC), Kyungpook National University, Daegu 41566, Republic of Korea.
Seung Pil YunDepartment of Pharmacology, Institute of Medical Science, College of Medicine, Gyeongsang National University, Jinju 52727, Republic of Korea.
Minkyeong KimDepartment of Neurology, Gyeongsang National University Hospital, Jinju 52727, Republic of Korea.ORCID 0000-0001-8376-867X

Funding

Gyeongsang National University Hospital GNUHBRIF-2021-0000National Research Foundation of Korea NRF-2021R1A4A3027122National Research Foundation of Korea NRF-2021R1F1A1050970National Research Foundation of Korea NRF-2023R1A2C2004516
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

astrocytehypoxianeuronal deathParkinson’s disease (PD)pre-formed fibril

Identifiers

PMID40149582
PMCPMC11940376

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.