Evidence map›Paper›PMID 40149425›Full record

ArticleGenes2025

A New Function of the DRD1 Gene: GnRH Secretion Regulation in Sheep Hypothalamic Neurons.

Manjun Zhai, Shaoqi Cao, Huihui Liang, Yifan Xie, Zongsheng Zhao

Abstract read
In one paragraph

Article in Genes, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Manjun ZhaiCollege of Animal Science, Xinjiang Agricultural University, Urumqi 830052, China.ORCID 0000-0003-3573-4664
Shaoqi CaoXinjiang Uygur Autonomous Region Animal Husbandry General Station, Urumqi 830001, China.
Huihui LiangXinjiang Uygur Autonomous Region Animal Husbandry General Station, Urumqi 830001, China.
Yifan XieCollege of Animal Science and Technology, Shihezi University, Shihezi 832003, China.
Zongsheng ZhaoCollege of Animal Science and Technology, Shihezi University, Shihezi 832003, China.

Funding

High-level Talent Cultivation Project of Xinjiang Agricultural University 2522GCCRCNatural Science Foundation of Xinjiang Uygur Autonomous Region 2023D01B34
6 · The paper itself

Abstract

backgroundDopamine (DA) is an important neurotransmitter that is widely present in the central nervous system. DA plays a crucial regulatory role in mammalian emotion, endocrine function, and reproduction through the activation of dopamine receptors. We compared the transcriptomes of hypothalamic tissues from Kazakh sheep during the nonbreeding season of anoestrus and during the nutrient-induced nonbreeding season of oestrus. Our research findings suggest that the dopamine receptor D1 (

methodsIn the present study, the expression of

resultsmoreover, the overexpression of the

conclusionsThe present study revealed that the

Indexed as

Gonadotropin-Releasing HormoneHypothalamusNeuronsReceptors, Dopamine D1AnimalsDopamineEstrusFemaleSheepDopamineGonadotropin-Releasing HormoneReceptors, Dopamine D1DRD1GnRHhypothalamicKazakh sheep

Identifiers

PMID40149425
PMCPMC11942299

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.