Evidence map›Paper›PMID 40149325›Full record

ArticleCancers2025

Genomic Signature for Initial Brain Metastasis Velocity (iBMV) in Non-Small-Cell Lung Cancer Patients: The Elusive Biomarker to Predict the Development of Brain Metastases?

Sarah E Glynn, Claire M Lanier, Ariel R Choi, Ralph D'Agostino, Michael Farris, Mohammed Abdulhaleem, Yuezhu Wang, Margaret Smith, Jimmy Ruiz, Thomas Lycan and 12 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Cancers, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

22 authors.

Sarah E GlynnDepartment of Radiation Oncology, Wake Forest University School of Medicine, Winston Salem, NC 27157, USA.
Claire M LanierDepartment of Radiation Oncology, Wake Forest University School of Medicine, Winston Salem, NC 27157, USA.ORCID 0000-0003-0127-9253
Ariel R ChoiDepartment of Radiation Oncology, Wake Forest University School of Medicine, Winston Salem, NC 27157, USA.
Ralph D'AgostinoDepartment of Biostatistics and Data Science, Wake Forest University School of Medicine, Winston Salem, NC 27157, USA.ORCID 0000-0002-3550-8395
Michael FarrisDepartment of Radiation Oncology, Wake Forest University School of Medicine, Winston Salem, NC 27157, USA.
Mohammed AbdulhaleemDepartment of Medicine, West Virginia University, Morgantown, WV 26506, USA.ORCID 0000-0002-4429-2178
Yuezhu WangDepartment of Molecular and Cellular Bioscience, Wake Forest University School of Medicine, Winston Salem, NC 27157, USA.
Margaret SmithDepartment of Molecular and Cellular Bioscience, Wake Forest University School of Medicine, Winston Salem, NC 27157, USA.
Jimmy RuizDepartment of Internal Medicine, Section of Hematology and Oncology, Wake Forest University School of Medicine, Winston Salem, NC 27157, USA.ORCID 0000-0002-7242-3315
Thomas LycanDepartment of Internal Medicine, Section of Hematology and Oncology, Wake Forest University School of Medicine, Winston Salem, NC 27157, USA.ORCID 0000-0001-9475-1558
William Jeffrey PettyDepartment of Internal Medicine, Section of Hematology and Oncology, Wake Forest University School of Medicine, Winston Salem, NC 27157, USA.
Christina K CramerDepartment of Radiation Oncology, Wake Forest University School of Medicine, Winston Salem, NC 27157, USA.
Stephen B TatterDepartment of Neurosurgery, Wake Forest University School of Medicine, Winston Salem, NC 27157, USA.
Adrian W LaxtonDepartment of Neurosurgery, Wake Forest University School of Medicine, Winston Salem, NC 27157, USA.ORCID 0000-0002-4631-5476
Jaclyn J WhiteDepartment of Neurosurgery, Wake Forest University School of Medicine, Winston Salem, NC 27157, USA.ORCID 0000-0003-4891-498X
Jing SuDepartment of Biostatistics and Health Data Science, Indiana University School of Medicine, Indianapolis, IN 46202, USA.
Christopher T WhitlowDepartment of Diagnostic Radiology, Wake Forest University School of Medicine, Winston Salem, NC 27157, USA.
David R Soto-PantojaDepartment of Cancer Biology, Wake Forest University School of Medicine, Winston Salem, NC 27157, USA.
Fei XingDepartment of Cancer Biology, Wake Forest University School of Medicine, Winston Salem, NC 27157, USA.ORCID 0000-0001-6350-0764
Yuming JiangDepartment of Radiation Oncology, Wake Forest University School of Medicine, Winston Salem, NC 27157, USA.
Michael ChanDepartment of Radiation Oncology, Wake Forest University School of Medicine, Winston Salem, NC 27157, USA.
Corbin A HelisDepartment of Radiation Oncology, Wake Forest University School of Medicine, Winston Salem, NC 27157, USA.

Funding

Tumor Tissue CoreP30CA012197 · NCI · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI Ruben A. Mesa · 1985 to 2026
$55.4M
CTSA K12 Program at Wake ForestK12TR004931 · NCATS · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI Nicholette D. Allred · 2024 to 2026
$2.3M
NCATS NIH HHS K12 TR004931NCI NIH HHS P30 CA012197
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

brain metastasesbrain surveillancegenetic biomarkersnext-generation sequencingnon-small-cell lung cancerradiotherapy

Identifiers

PMID40149325
PMCPMC11941343

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.