Evidence map›Paper›PMID 40149213›Full record

ArticleEntropy (Basel, Switzerland)2025

Practical Consequences of the Bias in the Laplace Approximation to Marginal Likelihood for Hierarchical Models.

Subhash R Lele, C George Glen, José Miguel Ponciano

Abstract read
In one paragraph

Article in Entropy (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Subhash R LeleDepartment of Mathematical and Statistical Sciences, University of Alberta, Edmonton, AB T6G 2R3, Canada.
C George GlenArchie Carr Center for Sea Turtle Research, Gainesville, FL 114000, USA.ORCID 0000-0002-4589-9705
José Miguel PoncianoDepartment of Biology, University of Florida, Gainesville, FL 114000, USA.ORCID 0000-0001-8457-7840

Funding

U.S. National Science Foundation 2052372.
6 · The paper itself

Abstract

Due to the high dimensional integration over latent variables, computing marginal likelihood and posterior distributions for the parameters of a general hierarchical model is a difficult task. The Markov Chain Monte Carlo (MCMC) algorithms are commonly used to approximate the posterior distributions. These algorithms, though effective, are computationally intensive and can be slow for large, complex models. As an alternative to the MCMC approach, the Laplace approximation (LA) has been successfully used to obtain fast and accurate approximations to the posterior mean and other derived quantities related to the posterior distribution. In the last couple of decades, LA has also been used to approximate the marginal likelihood function and the posterior distribution. In this paper, we show that the bias in the Laplace approximation to the marginal likelihood has substantial practical consequences.

Indexed as

biased estimating functionsdata cloningerrors in variablesMarkov Chain Monte Carlo

Identifiers

PMID40149213
PMCPMC11941402

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.