Evidence map›Paper›PMID 40149125›Full record

ReviewAntibiotics (Basel, Switzerland)2025

The Role of PI3k-Gamma Modulation in Bacterial Infection: A Review of the Literature and Selected Experimental Observations.

Daniel Sun, Alexandria Hoffman, Fatemeh Askarian, Elisabet Bjånes, Eric X Lin, Judith Varner, Victor Nizet

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Antibiotics (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Daniel SunSkaggs School of Pharmacy and Pharmaceutical Sciences, UC San Diego, La Jolla, CA 92093, USA.ORCID 0000-0001-7119-6045
Alexandria HoffmanDepartment of Pediatrics, UC San Diego, La Jolla, CA 92093, USA.ORCID 0000-0002-8208-8995
Fatemeh AskarianDepartment of Pediatrics, UC San Diego, La Jolla, CA 92093, USA.ORCID 0000-0002-7438-4671
Elisabet BjånesDepartment of Pediatrics, UC San Diego, La Jolla, CA 92093, USA.ORCID 0000-0002-2747-7699
Eric X LinDepartment of Pediatrics, UC San Diego, La Jolla, CA 92093, USA.ORCID 0009-0002-1134-7782
Judith VarnerBiomedical Sciences Graduate Program, UC San Diego, La Jolla, CA 92093, USA.ORCID 0000-0002-9251-0600
Victor NizetSkaggs School of Pharmacy and Pharmaceutical Sciences, UC San Diego, La Jolla, CA 92093, USA.ORCID 0000-0003-3847-0422

Funding

UCSD/SDSU IRACDAK12GM068524 · NIGMS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI TREJO, JOANN · 2003 to 2025
$24.4M
GRADUATE TRAINING IN CELLULAR &MOLECULAR PHARMACOLOGYT32GM007752 · NIGMS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI BROWN, JOAN HELLER, HANDEL, TRACY M · 1985 to 2023
$13.5M
Role of PI3Kinase in Tumor Progression and MetastasisR01CA167426 · NCI · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI Judith A VARNER · 2012 to 2026
$5.8M
NCI NIH HHS R01 CA167426NIGMS NIH HHS K12 GM068524NIGMS NIH HHS T32 GM007752NIH HHS 1R01AI176554-04A1NIH HHS 1R01CA226909-04A1NIH HHS 1T32GM153123-01A1
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

drug repurposinghost–pathogen interactionsPI3kStaph aureus

Identifiers

PMID40149125
PMCPMC11939471

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.