Evidence map›Paper›PMID 40149088›Full record

ReviewAntibiotics (Basel, Switzerland)2025

Suppressive Antibiotic Therapy in Prosthetic Joint Infections: A Contemporary Overview.

Hajer Harrabi, Eloïse Meyer, Nathalie Dournon, Frédérique Bouchand, Christel Mamona Kilu, Véronique Perronne, Karim Jaffal, Emma d'Anglejan, Clara Duran, Aurélien Dinh

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Antibiotics (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Hajer HarrabiInfectious Disease Department, University Hospital R. Poincaré, Assistance Publique des Hôpitaux de Paris, Versailles Paris Saclay University, 104 Bd R. Poincaré, 92380 Garches, France.
Eloïse MeyerInfectious Disease Department, University Hospital R. Poincaré, Assistance Publique des Hôpitaux de Paris, Versailles Paris Saclay University, 104 Bd R. Poincaré, 92380 Garches, France.
Nathalie DournonInfectious Disease Department, University Hospital R. Poincaré, Assistance Publique des Hôpitaux de Paris, Versailles Paris Saclay University, 104 Bd R. Poincaré, 92380 Garches, France.
Frédérique BouchandInfectious Disease Department, University Hospital R. Poincaré, Assistance Publique des Hôpitaux de Paris, Versailles Paris Saclay University, 104 Bd R. Poincaré, 92380 Garches, France.
Christel Mamona KiluInfectious Disease Department, University Hospital R. Poincaré, Assistance Publique des Hôpitaux de Paris, Versailles Paris Saclay University, 104 Bd R. Poincaré, 92380 Garches, France.
Véronique PerronneInfectious Disease Department, University Hospital R. Poincaré, Assistance Publique des Hôpitaux de Paris, Versailles Paris Saclay University, 104 Bd R. Poincaré, 92380 Garches, France.
Karim JaffalInfectious Disease Department, University Hospital R. Poincaré, Assistance Publique des Hôpitaux de Paris, Versailles Paris Saclay University, 104 Bd R. Poincaré, 92380 Garches, France.
Emma d'AnglejanInfectious Disease Department, University Hospital R. Poincaré, Assistance Publique des Hôpitaux de Paris, Versailles Paris Saclay University, 104 Bd R. Poincaré, 92380 Garches, France.
Clara DuranInfectious Disease Department, University Hospital R. Poincaré, Assistance Publique des Hôpitaux de Paris, Versailles Paris Saclay University, 104 Bd R. Poincaré, 92380 Garches, France.
Aurélien DinhInfectious Disease Department, University Hospital R. Poincaré, Assistance Publique des Hôpitaux de Paris, Versailles Paris Saclay University, 104 Bd R. Poincaré, 92380 Garches, France.ORCID 0000-0002-5843-4819

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The management of prosthetic joint infections (PJIs) poses significant challenges, requiring a multidisciplinary approach involving surgical, microbiological, and pharmacological expertise. Suppressive antibiotic therapy (SAT) has emerged as a viable option in cases where curative interventions are deemed unfeasible. This review provides an updated synthesis of recent evidence on SAT, including its indications, efficacy, practical considerations, and associated challenges. We aim to highlight the nuances of this therapeutic approach, discuss the factors influencing its success, and offer future directions for research to optimize patient outcomes.

Indexed as

PJISATsuppressivesurgery

Identifiers

PMID40149088
PMCPMC11939255

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.