Evidence map›Paper›PMID 40149003›Full record

ArticleJournal of biomedical semantics2025

Semantics in action: a guide for representing clinical data elements with SNOMED CT.

Julien Ehrsam, Christophe Gaudet-Blavignac, Mirjam Mattei, Monika Baumann, Christian Lovis

Abstract read
In one paragraph

Article in Journal of biomedical semantics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Julien Ehrsam *Division of Medical Information Sciences, Diagnostic Department, University Hospitals of Geneva, Rue Gabrielle-Perret-Gentil 4, Geneva, 1205, Switzerland. Julien.Ehrsam@hug.ch.
Christophe Gaudet-Blavignac *Division of Medical Information Sciences, Diagnostic Department, University Hospitals of Geneva, Rue Gabrielle-Perret-Gentil 4, Geneva, 1205, Switzerland.
Mirjam MatteiDivision of Medical Information Sciences, Diagnostic Department, University Hospitals of Geneva, Rue Gabrielle-Perret-Gentil 4, Geneva, 1205, Switzerland.
Monika BaumannDivision of Medical Information Sciences, Diagnostic Department, University Hospitals of Geneva, Rue Gabrielle-Perret-Gentil 4, Geneva, 1205, Switzerland.
Christian LovisDivision of Medical Information Sciences, Diagnostic Department, University Hospitals of Geneva, Rue Gabrielle-Perret-Gentil 4, Geneva, 1205, Switzerland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundClinical data is abundant, but meaningful reuse remains lacking. Semantic representation using SNOMED CT can improve research, public health, and quality of care. However, the lack of applied guidelines to industrialise the process hinders sustainability and reproducibility. This work describes a guide for semantic representation of data elements with SNOMED CT, addressing challenges encountered during its application. The representation of the institutional data warehouse started with the guidelines proposed by SNOMED International and other groups. However, the application at large scale of manual expert-driven representation led to the development of additional rules.

resultsAn eight-rule step-by-step guide was developed iteratively through focus groups. Continuously refined by usage and growing coverage, they are tested in practice to ensure they achieve the desired outcome. All rules prioritize maintaining semantic accuracy, which is the main goal of our strategy. They are divided into four groups which apply to understanding the data correctly (Context), and to using SNOMED CT properly (Single concepts first, Approved post-coordination, Extending post-coordination).

conclusionsThis work provides a practical framework for semantic representation using SNOMED CT, enabling greater accuracy and consistency by promoting a common method. While addressing challenges of large-scale implementation, the guide supports the drive from data centric models to a semantic centric approach, leveraging interoperability and more effective reuse of clinical data.

Indexed as

SemanticsSystematized Nomenclature of MedicineGuidelines as TopicHumansData warehouseKnowledge representationManual semantic annotationSemantic interoperabilitySNOMED CT

Identifiers

PMID40149003
PMCPMC11948947

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.