Evidence map›Paper›PMID 40148844›Full record

Trial reportBMC pregnancy and childbirth2025

Validation of the intolerance of uncertainty scale-12 in a sample of pregnant people.

Kayla Costello, C Alix Timko, Drew Anderson, Julia M Hormes

Registry-linked trialAbstract readRandomized Controlled TrialValidation Study
In one paragraph

Trial report in BMC pregnancy and childbirth, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06129461 (A Single Session Self-guided Acceptance-based Digital Intervention Targeting Food Cravings as Predictors of Disordered Eating in Pregnant People), which is not on this map. Not yet cited in PubMed.

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0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06129461 naunknown statusnot on this map

A Single Session Self-guided Acceptance-based Digital Intervention Targeting Food Cravings as Predictors of Disordered Eating in Pregnant People

TypeinterventionalSponsorUniversity at AlbanyRan2023 to 2024Enrolled130ConditionsPregnancy Weight Gain, Eating Disorders, Perinatal Problems, Binge EatingArmsSingle-session acceptance-based online workshop targeting food cravings as predictors of loss of control and binge eating in pregnancy
3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Kayla CostelloDepartment of Psychology, University at Albany, State University of New York, Social Sciences, 1400 Washington Avenue, Social Sciences, 399, Albany, NY, 12222, USA.
C Alix TimkoEating Disorder Assessment and Treatment Program, Department of Child and Adolescent Psychiatry and Behavioral Sciences, Children's Hospital of Philadelphia, Philadelphia, PA, USA.
Drew AndersonDepartment of Psychology, University at Albany, State University of New York, Social Sciences, 1400 Washington Avenue, Social Sciences, 399, Albany, NY, 12222, USA.
Julia M HormesDepartment of Psychology, University at Albany, State University of New York, Social Sciences, 1400 Washington Avenue, Social Sciences, 399, Albany, NY, 12222, USA. jhormes@albany.edu.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundIntolerance of uncertainty (IU) has been proposed as a transdiagnostic mechanism driving anxiety, depression, and eating disorder symptoms. Pregnancy is a time of significant uncertainty, yet few studies have examined the measurement of IU and its impacts on pregnant people. The current study aimed to examine the psychometric performance of two versions of the Intolerance of Uncertainty Scale (IUS-27 and IUS-12) and their associations with psychopathologies common in pregnancy.

methodsThis study is a secondary analysis of participants (n = 254) recruited for a larger study of a single-session intervention targeting disordered eating in pregnancy. We examined fit of participant baseline data with IUS-27 and IUS-12 factor structures using confirmatory factor analyses. We also assessed associations between IU and emotion dysregulation and depression and eating disorder symptoms, controlling for age, parity, and perceived social status.

resultsThe IUS-12 provided superior fit to the data (CFI = 0.95; TLI = 0.93; RMSEA = 0.09) compared to the IUS-27. The IUS-12 was significantly (all p < 0.05) correlated with measures of emotion dysregulation (r = 0.67), depression (r = 0.58), and eating disorders (r = 0.37). Inhibitory IU rather than prospective IU was generally significantly associated with greater psychopathology (ß range = 0.46 - 3.51, p's < 0.01).

conclusionsResults from this study provide initial support for the IUS-12 as a valid measure of IU in pregnant people and suggest that IU is strongly associated with measures of depression, emotion dysregulation, and eating disorder behaviors in this population. Severe psychological distress in pregnancy has been linked to complications in gestation and delivery and overall poor birth outcomes. Clinicians and doctors should consider using the IUS-12 as a general measure of psychological distress among pregnant patients.

trial registrationThe trial from which these data were drawn is registered at clinicaltrials.gov, NCT06129461 (registered on November 10, 2023).

Indexed as

Feeding and Eating DisordersPregnancy ComplicationsPregnant PeopleAdultAnxietyDepressionFemaleHumansPregnancyPsychiatric Status Rating ScalesPsychometricsReproducibility of ResultsSurveys and QuestionnairesUncertaintyYoung AdultConfirmatory factor analysisFactor structureIntolerance of uncertaintyIntolerance of uncertainty scalePregnancy

Identifiers

PMID40148844
PMCPMC11948860

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.