ArticleBMC plant biology2025
Amino acid metabolism pathways as key regulators of nitrogen distribution in tobacco: insights from transcriptome and WGCNA analyses.
Article in BMC plant biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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Who cites it
9 citing papers in PubMed.
- Developmental Dynamics of Bioactive Compound Accumulation During Vegetative Growth in Thymus daenensis Čelak.Chemistry & biodiversity · 2026Article
- Comparative transcriptome analysis reveals stress-response pathways as key drivers of nitrogen use efficiency in tobacco under low-nitrogen conditions.BMC plant biology · 2026Article
- Coordinated regulation of amino acid metabolism and transport in cereal nitrogen remobilization for grain filling.Frontiers in plant science · 2026Review
- Integration of Non-Invasive Micro-Test Technology andInternational journal of molecular sciences · 2025Article
- Study on the Influence Mechanism of the Rhizosphere Soil Microbial Community and Physicochemical Factors on the Occurrence of PepperMicroorganisms · 2025Article
- Genome-Wide Screening for MYB Transcription Factors Involved in Flavonoid Glycoside Biosynthesis inGenes · 2025Article
- Article
- Comprehensive Identification of Key Genes Responsible for Leaf Senescence of Rice (Plants (Basel, Switzerland) · 2025Article
- The molecular mechanism of leaf margin fission inFrontiers in plant science · 2025Article
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Authors and funding
12 authors.
Funding
Abstract
BACKGROUND AND
aimNitrogen (N) is crucial for plant growth and is distributed across various N morphologies within plant organs. However, the mechanisms controlling the distribution of these N morphologies are not fully understood. This study investigated key amino acid (AA) biosynthesis pathways regulating N distribution and their impact on plant physiology and growth.
methodsWe examined N distribution in the leaves, stems, and roots of two tobacco cultivars (Hongda and K326) under different N treatments at 75, and 100 days after transplanting (DAT). Transcriptome analysis was performed at 75 and 100 DAT to explore N distribution and AA metabolism pathways. Weighted gene co-expression network analysis (WGCNA) identified pathways regulating N distribution, and the Mantel test assessed the impact of N treatments, growth stages, and cultivars on N distribution.
resultsStatistically significant differences in N distribution were observed across environmental conditions, growth stages, cultivars, and plant organs (p < 0.05). WGCNA identified phenylalanine metabolism (ko00360), alanine, aspartate, and glutamate metabolism (ko00250), and glycine, serine, and threonine metabolism (ko00260) pathways regulating the distribution of N
conclusionThis study elucidates the mechanisms regulating N distribution in tobacco, emphasizing the role of AA metabolism pathways. These findings are essential for improving N utilization and optimizing N management practices, ultimately enhancing crop productivity and supporting sustainable agricultural practices.
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