ReviewWorld journal of microbiology & biotechnology2025
Advances in vanillin synthesis: focusing on microbial synthesis pathways and prospects.
Review in World journal of microbiology & biotechnology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
4 citing papers in PubMed.
- Biosynthesis of vanillin glucoside inSynthetic and systems biotechnology · 2027Article
- Synthesis and evaluation of vanillin-based sulfonates as potent α-glucosidase inhibitors through in vitro, in vivo, and in silico approaches.Scientific reports · 2026Article
- Direct valorization of agricultural byproducts to vanillin by a synergistic Komagataella phaffii co-culture system.Biotechnology for biofuels and bioproducts · 2026Article
- Sensory Evaluation of Vanillin Obtained by Fungi in the Solid-State Fermentation from Agri-Food Industry By-Products.Molecules (Basel, Switzerland) · 2025Article
Corrections and comments
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Authors and funding
7 authors.
Funding
Abstract
Vanillin, often referred to as the 'Queen of Spices', is extensively utilized in the food industry, pharmaceutical manufacturing, cosmetic formulations, agricultural crop protection, and tobacco processing owing to its distinctive flavor properties. In recent years, the biosynthesis of vanillin from suitable substrates through microbial transformation technology has emerged as a prominent research topic, driven by the increasing global demand for "green and natural" products and the growing awareness of environmental protection. In this review, we examine the three primary synthesis methods of vanillin: natural extraction, chemical synthesis, and biosynthesis, and elucidate the principles, developmental history, and current technological advancements of each approach. Building on this foundation, the review emphasizes recent advancements in vanillin biosynthesis, analyzes the specific applications, technological innovations, and potential advantages of microbial conversion strategies in vanillin production, and addresses the challenges of low conversion efficiency and weak strain tolerance in microbial synthesis. Furthermore, this review offers insights into the future development trends of vanillin biosynthesis. It proposes research recommendations for optimizing microbial strains, enhancing bioconversion efficiency, and achieving industrial-scale production, aiming to serve as a valuable reference for the continued advancement of vanillin biosynthesis technology.
Indexed as
Identifiers
40148696What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.