Evidence map›Paper›PMID 40148587›Full record

ArticleJournal of medical ultrasonics (2001)2025

The role of ultrasound in assessment and prediction of the efficacy of preoperative targeted therapy for gastrointestinal mesenchymal tumors compared with pathology.

Ping Yang, XiuJun Li, ChonQing Chen, Jing Sun, JiangYan Yin, TiaTian Wang, XingYe Wu, Jun Zhang, XueMei He

Abstract readComparative Study
PubMed Publisher
In one paragraph

Article in Journal of medical ultrasonics (2001), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Ping YangDepartment of Ultrasound, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China.
XiuJun LiDepartment of Pathology, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China.
ChonQing ChenDepartment of Ultrasound, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China.
Jing SunDepartment of Ultrasound, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China.
JiangYan YinDepartment of Ultrasound, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China.
TiaTian WangDepartment of Ultrasound, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China.
XingYe WuDepartment of Gastrointestinal Surgery, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China.
Jun ZhangDepartment of Gastrointestinal Surgery, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China.
XueMei HeDepartment of Ultrasound, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China. hexm@hospital.cqmu.edu.cn.ORCID http://orcid.org/0000-0002-3763-2007

Funding

Natural Science Foundation Project of Chongqing, Chongqing Science and Technology Commission CSTB2022NSCQ-MSX0133
6 · The paper itself

Abstract

purposeTo explore the value of ultrasound in efficacy assessment and prediction of preoperative targeted treatment for gastrointestinal stromal tumor (GIST), using pathological assessment as a reference.

methodsA total of 35 GIST patients with preoperative targeted therapy were included in this retrospective study. The efficacy was evaluated using both ultrasound and pathology. Spearman correlation analysis and Kappa test were used to analyze the correlation and consistency between the evaluation results of ultrasound and pathology. Univariate analysis was used to obtain relevant predictive indicators of treatment response, which were then included in ordered logistic regression analysis to screen for independent predictive factors.

resultsIn the 35 patients who underwent targeted therapy, the results of pathological assessment suggested complete response in one patient, high response in 11 patients, partial response in 15 patients, and no response in eight patients; the results of ultrasound assessment were complete response in zero patients, partial response in 20 patients, stable disease in nine patients, and progressive disease in six patients. Preoperative ultrasound evaluation of targeted therapy for GIST was moderately consistent and highly correlated with the results of postoperative pathological evaluation. Short-to-length diameter (S/L) ratio and tumor shape were independent predictors of treatment response.

conclusionUltrasound is potentially beneficial for evaluating and predicting the response to treatment of GIST.

Indexed as

Gastrointestinal NeoplasmsGastrointestinal Stromal TumorsAdultAgedAged, 80 and overFemaleHumansMaleMiddle AgedPredictive Value of TestsPreoperative CareRetrospective StudiesTreatment OutcomeUltrasonographyEfficacy evaluationGastrointestinal stromal tumorPathological assessmentPreoperative targeted therapyUltrasound

Identifiers

PMID40148587

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.