Evidence map›Paper›PMID 40148322›Full record

ArticleNature communications2025

Keratin-72 restricts HIV-1 infection in resting CD4

Yang He, Meng Xu, Jiayue Ouyang, Li Zhao, Tiankui Ma, Xiaowei Zhang, Ruolin Wang, Hong Shang, Guoxin Liang

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Nature communications, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Article
  3. HIV-1 latency: From acquaintance to confidant.Journal of virus eradication · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Yang He *Key Laboratory of AIDS Immunology of Ministry of Health, Department of Laboratory Medicine, The First Hospital of China Medical University, Shenyang, China.
Meng Xu *Key Laboratory of AIDS Immunology of Ministry of Health, Department of Laboratory Medicine, The First Hospital of China Medical University, Shenyang, China.
Jiayue OuyangKey Laboratory of AIDS Immunology of Ministry of Health, Department of Laboratory Medicine, The First Hospital of China Medical University, Shenyang, China.
Li ZhaoKey Laboratory of AIDS Immunology of Ministry of Health, Department of Laboratory Medicine, The First Hospital of China Medical University, Shenyang, China.
Tiankui MaCenter for Cell and Gene Therapy, The First Hospital of China Medical University, Shenyang, China.
Xiaowei ZhangKey Laboratory of AIDS Immunology of Ministry of Health, Department of Laboratory Medicine, The First Hospital of China Medical University, Shenyang, China.
Ruolin WangKey Laboratory of AIDS Immunology of Ministry of Health, Department of Laboratory Medicine, The First Hospital of China Medical University, Shenyang, China.
Hong ShangKey Laboratory of AIDS Immunology of Ministry of Health, Department of Laboratory Medicine, The First Hospital of China Medical University, Shenyang, China. hshang@cmu.edu.cn.ORCID http://orcid.org/0000-0001-5333-8943
Guoxin LiangKey Laboratory of AIDS Immunology of Ministry of Health, Department of Laboratory Medicine, The First Hospital of China Medical University, Shenyang, China. gxliang@cmu.edu.cn.ORCID http://orcid.org/0000-0003-1789-9094

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The accessory protein Vpx from the red-capped mangabey or mandrill SIV (SIV

Indexed as

CapsidCD4-Positive T-LymphocytesHIV-1HIV InfectionsIntermediate FilamentsAnimalsHEK293 CellsHumansKeratinsViral Regulatory and Accessory ProteinsVirus ReplicationKeratinsViral Regulatory and Accessory Proteins

Identifiers

PMID40148322
PMCPMC11950370

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.